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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Drd1
dopamine receptor D1
MGI:99578
40 phenotypes from 8 alleles in 13 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Drd1tm1(cre)Rpa/Drd1tm1(cre)Rpa
involves: 129S4/SvJaeSor * C57BL/6
abnormal behavior J:138586
decreased body size J:138586
Drd1tm1.1Mmsh/Drd1tm1.1Mmsh
Gng7tm1(cre)Mmsh/?
involves: C57BL/6N
normal behavior/neurological phenotype J:210178
impaired cued conditioning behavior J:210178
Drd1tm1Jcd/Drd1+
involves: 129S4/SvJae
abnormal contextual conditioning behavior J:67395
abnormal passive avoidance behavior J:67395
Drd1tm1Jcd/Drd1tm1Jcd
B6.129S4-Drd1tm1Jcd
increased startle reflex J:154428
Drd1tm1Jcd/Drd1tm1Jcd
B6.129S4-Drd1tm1Jcd/J
abnormal eye electrophysiology J:185955
abnormal vision J:185955
decreased physiological sensitivity to xenobiotic J:137069
decreased response to stress-induced hyperthermia J:137069
decreased susceptibility to xenobiotic induced morbidity/mortality J:137069
Drd1tm1Jcd/Drd1tm1Jcd
involves: 129S4/SvJae
abnormal contextual conditioning behavior J:67395
abnormal inhibitory learning J:102603
abnormal neuronal migration J:121219
abnormal passive avoidance behavior J:67395
abnormal spatial learning J:102600, J:102603
behavioral despair J:102600
decreased body size J:67395, J:102603
decreased locomotor activity J:102600
decreased vertical activity J:102600
impaired coordination J:102600
increased thigmotaxis J:102600
loss of GABAergic neurons J:121219
Drd1tm1Jcd/Drd1tm1Jcd
involves: 129S4/SvJae * C57BL/6
decreased body weight J:22076
decreased vertical activity J:22076
disheveled coat J:22076
hunched posture J:22076
postnatal growth retardation J:22076
premature death J:22076
Drd1tm1Stl/Drd1tm1Stl
involves: 129P2/OlaHsd
abnormal response/metabolism to endogenous compounds J:112986
decreased physiological sensitivity to xenobiotic J:112986
hyperactivity J:112986
impaired behavioral response to cocaine J:112986
increased exploration in new environment J:112986
Drd1tm1Stl/Drd1tm1Stl
involves: 129P2/OlaHsd * C57BL/6
decreased body size J:21603
decreased body weight J:21603
decreased brain size J:21603
decreased striatum size J:21603
hyperactivity J:21603
impaired behavioral response to xenobiotic J:21603
postnatal lethality, incomplete penetrance J:21603
Drd1tm1Stl/Drd1tm1Stl
involves: 129P2/OlaHsd * C57BL/6J
impaired behavioral response to cocaine J:127798
impaired behavioral response to xenobiotic J:127798
Drd1tm1Tono/Drd1tm1Tono
B6.129S-Drd1tm1Tono
abnormal synaptic plasticity J:143054
Drd1tm2.1Stl/Drd1tm2.1Stl
involves: C57BL/6
no abnormal phenotype detected J:211355
Drd1tm2.1Stl/Drd1tm2.1Stl
Tg(Pomc-cre)1Lowl/0
involves: C57BL/6 * FVB/N
decreased fear-related response J:211355
impaired contextual conditioning behavior J:211355
Drd1tm2.2Stl/Drd1tm2.2Stl
involves: C57BL/6
preweaning lethality, complete penetrance J:211355
Drd1tm2Rpa/Drd1tm2Rpa
involves: 129S4/SvJae * C57BL/6 * C57BL/6J
impaired behavioral response to cocaine J:121750
impaired conditioned place preference behavior J:121750

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory