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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Drd1
dopamine receptor D1
MGI:99578
69 phenotypes from 10 alleles in 17 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Drd1tm1(cre)Rpa/Drd1tm1(cre)Rpa
involves: 129S4/SvJaeSor * C57BL/6
abnormal behavior J:138586
decreased body size J:138586
Drd1tm1.1(IL2RA/Venus)Koba/Drd1+
B6.129S6-Drd1tm1.1(IL2RA/Venus)Koba
abnormal neuron morphology J:184374
abnormal operant conditioning behavior J:184374
normal behavior/neurological phenotype J:184374
Drd1tm1.1Mmsh/Drd1tm1.1Mmsh
Gng7tm1(cre)Mmsh/?
involves: C57BL/6N
normal behavior/neurological phenotype J:210178
impaired cued conditioning behavior J:210178
Drd1tm1Jcd/Drd1+
involves: 129S4/SvJae
abnormal contextual conditioning behavior J:67395
abnormal passive avoidance behavior J:67395
Drd1tm1Jcd/Drd1tm1Jcd
B6.129S4-Drd1tm1Jcd
increased startle reflex J:154428
Drd1tm1Jcd/Drd1tm1Jcd
B6.129S4-Drd1tm1Jcd/J
abnormal eye electrophysiology J:185955
abnormal vision J:185955
decreased physiological sensitivity to xenobiotic J:137069
decreased response to stress-induced hyperthermia J:137069
decreased sensitivity to xenobiotic induced morbidity/mortality J:137069
Drd1tm1Jcd/Drd1tm1Jcd
involves: 129S4/SvJae
abnormal contextual conditioning behavior J:67395
abnormal inhibitory learning J:102603
abnormal neuronal migration J:121219
abnormal passive avoidance behavior J:67395
abnormal spatial learning J:102600, J:102603
behavioral despair J:102600
decreased body size J:67395, J:102603
decreased vertical activity J:102600
hypoactivity J:102600
impaired coordination J:102600
increased thigmotaxis J:102600
loss of GABAergic neurons J:121219
Drd1tm1Jcd/Drd1tm1Jcd
involves: 129S4/SvJae * C57BL/6
decreased body weight J:22076
decreased vertical activity J:22076
disheveled coat J:22076
hunched posture J:22076
postnatal growth retardation J:22076
premature death J:22076
Drd1tm1Stl/Drd1tm1Stl
involves: 129P2/OlaHsd
abnormal response/metabolism to endogenous compounds J:112986
decreased physiological sensitivity to xenobiotic J:112986
hyperactivity J:112986
impaired behavioral response to cocaine J:112986
Drd1tm1Stl/Drd1tm1Stl
involves: 129P2/OlaHsd * C57BL/6
decreased body size J:21603
decreased body weight J:21603
decreased brain size J:21603
decreased striatum area J:21603
hyperactivity J:21603
impaired behavioral response to xenobiotic J:21603
postnatal lethality, incomplete penetrance J:21603
Drd1tm1Stl/Drd1tm1Stl
involves: 129P2/OlaHsd * C57BL/6J
impaired behavioral response to cocaine J:127798
impaired behavioral response to xenobiotic J:127798
Drd1tm1Tono/Drd1tm1Tono
B6.129P2-Drd1tm1Tono
abnormal synaptic plasticity J:143054
Drd1tm2.1Stl/Drd1tm2.1Stl
involves: C57BL/6
no abnormal phenotype detected J:211355
Drd1tm2.1Stl/Drd1tm2.1Stl
Tg(Pomc-cre)1Lowl/0
involves: C57BL/6 * FVB/N
decreased fear-related response J:211355
impaired contextual conditioning behavior J:211355
Drd1tm2.2Stl/Drd1tm2.2Stl
involves: C57BL/6
preweaning lethality, complete penetrance J:211355
Drd1tm2Jcd/Drd1+
either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * CD-1)
no abnormal phenotype detected J:120582
Drd1tm2Jcd/Drd1+
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S4/SvJae * BALB/c * CD-1 * FVB/N
abnormal forebrain morphology J:120582
abnormal hippocampus morphology J:120582
abnormal nervous system physiology J:120582
abnormal posture J:120582
abnormal striatum morphology J:120582
bradykinesia J:120582
decreased brain size J:120582
decreased brain weight J:120582
decreased forebrain size J:120582
decreased forebrain volume J:120582
decreased pulmonary respiratory rate J:120582
dystonia J:120582
gliosis J:120582
impaired balance J:120582
impaired righting response J:120582
myoclonus J:120582
postnatal lethality, complete penetrance J:120582
Drd1tm2Jcd/Drd1+
Tg(Camk2a-cre)2Gsc/0
involves: 129S4/SvJae * FVB/N
abnormal brain wave pattern J:120070
abnormal cerebral cortex morphology J:120070
abnormal dentate gyrus morphology J:120070
abnormal forebrain morphology J:120070
abnormal microglial cell physiology J:120070
abnormal nervous system morphology J:120070
abnormal nervous system physiology J:120070
astrocytosis J:120070
decreased body weight J:120070
decreased brain size J:120070
decreased brain weight J:120070
decreased hippocampus volume J:120070
decreased striatum area J:120070
dystonia J:120070
enlarged lateral ventricles J:120070
hyperactivity J:120070
increased vertical activity J:120070
limb grasping J:120070
seizures J:120070
trunk curl J:120070
Drd1tm2Rpa/Drd1tm2Rpa
involves: 129S4/SvJae * C57BL/6 * C57BL/6J
impaired behavioral response to cocaine J:121750
impaired conditioned place preference behavior J:121750

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory