Arrb2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arrb2
arrestin, beta 2
MGI:99474

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arrb2^{tm1.1(KOMP)Vlcg}/Arrb2⁺ B6N(Cg)-Arrb2^{tm1.1(KOMP)Vlcg}/J	increased circulating free fatty acids level	J:211773
Arrb2^{tm1.1(KOMP)Vlcg}/Arrb2^{tm1.1(KOMP)Vlcg} B6N(Cg)-Arrb2^{tm1.1(KOMP)Vlcg}/J	abnormal lens morphology	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating phosphate level	J:211773
	increased grip strength	J:211773
Arrb2^tm1Rjl/Arrb2^tm1Rjl involves: 129X1/SvJ * C57BL/6	abnormal body temperature homeostasis	J:59162
	abnormal circulating tumor necrosis factor level	J:112607
	abnormal lymphocyte physiology	J:76872
	increased acute inflammation	J:112607
	increased chemically-elicited antinociception	J:59162
	increased circulating interleukin-6 level	J:112607
	increased interleukin-6 secretion	J:112607
	increased interleukin-12b secretion	J:112607
	increased susceptibility to endotoxin shock	J:112607
	increased tumor necrosis factor secretion	J:112607

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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