Mc1r Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mc1r
melanocortin 1 receptor
MGI:99456

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
A/A Mc1r^E-tob/Mc1r⁺ M. m. domesticus poschiavinus	abnormal coat/hair pigmentation	J:22593
A/A Mc1r^E-tob/Mc1r⁺ M. m. domesticus poschiavinus	darkened coat color	J:22593
A/A Mc1r^E-tob/Mc1r^E-tob M. m. domesticus poschiavinus	abnormal coat/hair pigmentation	J:22593
A/A Mc1r^E-tob/Mc1r^E-tob M. m. domesticus poschiavinus	darkened coat color	J:22593
a/A Mc1r^e/Mc1r^e Pomc^tm1Sora/Pomc^tm1Sora Tg(MC1R)1Jkn/? involves: 129S6/SvEvTac * C57BL/6Ha	abnormal hair follicle pheomelanosome pheomelanin content	J:129904
	yellow coat color	J:129904
a/a Mc1r^e/Mc1r^e Pomc^tm1Sora/Pomc^tm1Sora Tg(MC1R)1Jkn/? involves: 129S6/SvEvTac * C57BL/6Ha	abnormal hair follicle pheomelanosome pheomelanin content	J:129904
	yellow coat color	J:129904
A^y-Jkn/A Mc1r^e/Mc1r^e involves: C57BL/6Ha * C57BL/6N	yellow coat color	J:129904
A^y-Jkn/A Mc1r^e/Mc1r^e Tg(MC1R)1Jkn/0 involves: C57BL/6Ha * C57BL/6N	yellow coat color	J:129904
Adamts20^bt/Adamts20^bt Mc1r^e/Mc1r^e involves: C57BL/6Ha * DBA/2J	belted	J:5110
	yellow coat color	J:5110
Ednrb^s/Ednrb^s Mc1r^e/Mc1r^e Not Specified	white spotting	J:5110
Ednrb^s/Ednrb^s Mc1r^e/Mc1r^e Not Specified	yellow coat color	J:5110
Mc1r^e/Mc1r^e Mlph^ln/Mlph^ln Not Specified	diluted coat color	J:5110
Mc1r^e/Mc1r^e Pepd^dal/Pepd^dal involves: C57BL/6J * CBA/J	decreased body size	J:143333
Mc1r^e/Mc1r^e Pepd^dal/Pepd^dal involves: C57BL/6J * CBA/J	yellow coat color	J:143333
Mc1r^e/Mc1r^e Tg(KRT14-Kitl)1Takk/0 involves: C57BL/6 * SJL	abnormal melanogenesis	J:112959
Mc1r^e/Mc1r^e Xpc^tm1Brd/Xpc^tm1Brd Tg(KRT14-Kitl)1Takk/0 involves: 129S7/SvEvBrd * C57BL/6 * SJL	increased squamous cell carcinoma incidence	J:112959
	increased tumor incidence	J:112959
	skin lesions	J:112959
	thick epidermis	J:112959
	weight loss	J:112959
Mc1r^tm1.1Mymi/Mc1r^tm1.1Mymi Tg(KRT14-rtTA)F42Efu/0 Tg(tetO-EDN1,-lacZ)9Mhus/0 Tg(Tyr-cre/ERT2)13Bos/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac * FVB	abnormal epidermal melanocyte morphology	J:231435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23