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Mammalian Phenotype Ontology Annotations
Query Results - Summary
tight junction protein 1
38 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
involves: C57BL/6 * C57BL/6N
normal no abnormal phenotype detected J:226210
involves: C57BL/6 * C57BL/6N * DBA/2
abnormal glomerular filtration barrier morphology J:226210
abnormal kidney morphology J:226210
abnormal kidney pelvis morphology J:226210
abnormal podocyte foot process morphology J:226210
abnormal podocyte slit diaphragm morphology J:226210
absent podocyte slit diaphragm J:226210
albuminuria J:226210
detached podocyte J:226210
dilated renal tubules J:226210
fused podocyte foot processes J:226210
glomerulosclerosis J:226210
granular kidney J:226210
increased renal glomerulus basement membrane thickness J:226210
increased urine protein level J:226210
kidney papillary atrophy J:226210
pale kidney J:226210
podocyte foot process effacement J:226210
postnatal growth retardation J:226210
renal cast J:226210
no abnormal phenotype detected J:222380
abnormal developmental vascular remodeling J:222380
abnormal embryonic tissue morphology J:222380
abnormal extraembryonic tissue morphology J:222380
abnormal notochord morphology J:222380
abnormal placental labyrinth vasculature morphology J:222380
abnormal visceral yolk sac morphology J:222380
abnormal vitelline vascular remodeling J:222380
abnormal vitelline vasculature morphology J:222380
decreased embryo size J:222380
dilated allantois J:222380
embryonic growth retardation J:222380
embryonic lethality during organogenesis, complete penetrance J:222380
failure of chorioallantoic fusion J:222380
failure of initiation of embryo turning J:222380
increased allantois apoptosis J:222380
increased embryonic tissue cell apoptosis J:222380
increased neural tube apoptosis J:222380
Not Specified
no abnormal phenotype detected J:205841

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory