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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tgfb2
transforming growth factor, beta 2
MGI:98726
35 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Cdkn2atm1(GFP)Cjs/Cdkn2atm1(GFP)Cjs
Tgfb2tm1Doe/Tgfb2+
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
primary vitreous hyperplasia J:149526
Cdkn2atm1(GFP)Cjs/Cdkn2atm1(GFP)Cjs
Tgfb2tm1Doe/Tgfb2tm1Doe
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6
primary vitreous hyperplasia J:149526
Cdkn2atm1Cjs/Cdkn2a+
Tgfb2tm1Doe/Tgfb2tm1Doe
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
primary vitreous hyperplasia J:149526
Cdkn2atm1Sxs/Cdkn2a+
Tgfb2tm1Doe/Tgfb2tm1Doe
involves: 129/Sv * 129P2/OlaHsd * C57BL/6
primary vitreous hyperplasia J:149526
Ext1tm1Yama/Ext1+
H2afvTg(Wnt1-cre)11Rth/0
Tgfb2tm1Doe/Tgfb2+
B6.Cg-Tgfb2tm1Doe H2afvTg(Wnt1-cre)11Rth Ext1tm1Yama
abnormal aqueous drainage system morphology J:152572
abnormal canal of Schlemm morphology J:152572
abnormal trabecular meshwork morphology J:152572
normal mortality/aging J:152572
ocular hypertension J:152572
Fbn1tm1Hcd/Fbn1+
Tgfb2tm1Doe/Tgfb2+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
abnormal aorta wall morphology J:188799
aortic aneurysm J:188799
dilated aorta bulb J:188799
normal growth/size/body region phenotype J:188799
Tg(MMTV-TGFBR2)7Hlm/0
involves: C57BL/6 * DBA
abnormal lactation J:46432
mammary gland alveolar hyperplasia J:46432
Tg(MMTV-TGFBR2)7Hlm/Tg(MMTV-TGFBR2)7Hlm
involves: C57BL/6 * DBA
abnormal involution of the mammary gland J:85799
abnormal lactation J:46432
abnormal mammary gland growth during lactation J:85799
hypolactation J:85799
increased mammary adenocarcinoma incidence J:85799
mammary gland alveolar hyperplasia J:46432, J:85799
mammary gland hypoplasia J:85799
Tg(MMTV-TGFBR2)7Hlm/?
Tg(MMTVTGFA)29Rjc/?
involves: C57BL/6 * DBA
increased mammary adenocarcinoma incidence J:85799
Tgfb2tm1Doe/Tgfb2+
Tgfb3tm1Doe/Tgfb3+
involves: 129P2/OlaHsd
abnormal enterocyte apoptosis J:76342
abnormal small intestinal villus morphology J:76342
Tgfb2tm1Doe/Tgfb2+
Tgfb3tm1Doe/Tgfb3tm1Doe
involves: 129P2/OlaHsd
normal limbs/digits/tail phenotype J:76541
normal vision/eye phenotype J:105113
Tgfb2tm1Doe/Tgfb2tm1Doe
Tgfb3tm1Doe/Tgfb3+
involves: 129P2/OlaHsd
abnormal cartilage development J:76541
abnormal cornea morphology J:105113
abnormal eye posterior chamber morphology J:105113
abnormal interdigital cell death J:76541
abnormal lens epithelium morphology J:105113
abnormal retinal inner nuclear layer morphology J:105113
abnormal retinal neuronal layer morphology J:105113
decreased corneal stroma thickness J:105113
decreased retinal apoptosis J:105113
interdigital webbing J:76541
Tgfb2tm1Doe/Tgfb2tm1Doe
Tgfb3tm1Doe/Tgfb3tm1Doe
involves: 129P2/OlaHsd
abnormal cartilage development J:76541
abnormal chondrocyte morphology J:76541
abnormal cornea morphology J:105113
abnormal digit development J:76541
abnormal eye posterior chamber morphology J:105113
abnormal interdigital cell death J:76541
abnormal lens epithelium morphology J:105113
abnormal retinal apoptosis J:105113
abnormal retinal inner nuclear layer morphology J:105113
abnormal retinal neuronal layer morphology J:105113
decreased cornea thickness J:105113
decreased corneal stroma thickness J:105113
interdigital webbing J:76541

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory