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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
MGI:98282
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Runx1tm3Spe/Runx1tm3Spe
Spi1tm2.1Dgt/Spi1tm2.1Dgt
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA
decreased B cell number J:131217
decreased thymus weight J:131217
increased granulocyte number J:131217
increased spleen weight J:131217
Spi1tm1Ram/Spi1tm1Ram
Tg(SOD1*G93A)1Gur/0
involves: 129S2/SvPas * C57BL/6 * SJL
decreased motor neuron number J:116087
normal growth/size/body region phenotype J:116087
motor neuron degeneration J:116087
premature death J:116087
Spi1tm1Sing/Spi1+
Spibtm1Mcs/Spib+
involves: 129S/SvEv * 129X1/SvJ
abnormal spleen germinal center morphology J:88257
decreased B cell proliferation J:88257
normal hematopoietic system phenotype J:88257
Spi1tm1Sing/Spi1+
Spibtm1Mcs/Spibtm1Mcs
involves: 129S/SvEv * 129X1/SvJ
abnormal B cell differentiation J:88257
abnormal immature B cell morphology J:88257
absent spleen germinal center J:88257
decreased B cell number J:88257
decreased B cell proliferation J:88257
normal immune system phenotype J:88257
increased B cell apoptosis J:88257
Spi1tm1Sing/Spi1tm1Sing
Spibtm1Mcs/Spibtm1Mcs
involves: 129S/SvEv * 129X1/SvJ
lethality throughout fetal growth and development, complete penetrance J:88257

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory