Rps6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rps6
ribosomal protein S6
MGI:98159

20 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rps6^tm1Gtho/Rps6⁺ Tg(KRT5-cre)5132Jlj/0 involves: 129P2/OlaHsd * C57BL/6J * DBA/2J	abnormal epidermal pigmentation	J:139244
	darkened coat color	J:139244
	increased ear pigmentation	J:139244
	increased foot pad pigmentation	J:139244
	increased tail pigmentation	J:139244
Rps6^tm1Gtho/Rps6⁺ Tg(Mitf-cre)7114Gsb/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal dermal pigmentation	J:139244
	abnormal epidermal pigmentation	J:139244
	decreased skin pigmentation	J:139244
	decreased tail pigmentation	J:139244
	reduced foot pad pigmentation	J:139244
Rps6^tm1Gtho/Rps6^tm1Gtho Tg(Mx1-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal cell cycle	J:62795
	abnormal cell morphology	J:62795
	impaired liver regeneration	J:62795
Rps6^tm1Om/Rps6^tm1Om involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal cell cycle	J:100952
	abnormal cell morphology	J:100952
	abnormal cell physiology	J:100952
	abnormal hepatocyte morphology	J:100952
	abnormal pancreatic beta cell morphology	J:100952
	abnormal pancreatic islet morphology	J:100952
	decreased circulating insulin level	J:100952
	decreased insulin secretion	J:100952
	impaired glucose tolerance	J:100952
	increased insulin sensitivity	J:100952

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23