Rel Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rel
reticuloendotheliosis oncogene
MGI:97897

22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nfkb1^tm1Bal/Nfkb1^tm1Bal Rel^tm1Grd/Rel^tm1Grd involves: 129P2/OlaHsd * 129S1/Sv	abnormal immune system physiology	J:113514
	decreased interleukin-12 secretion	J:113514
Rel^tm1Grd/Rel^tm1Grd Rela^tm1Bal/Rela^tm1Bal B6.129S-Rel^tm1Grd Rela^tm1Bal	abnormal erythropoiesis	J:111325
	abnormal monocyte differentiation	J:111325
	decreased common myeloid progenitor cell number	J:111325
	embryonic lethality during organogenesis, complete penetrance	J:111325
	normal hematopoietic system phenotype	J:111325
	hyperchromasia	J:111325
	increased granulocyte number	J:111325
	increased hepatocyte apoptosis	J:111325
	internal hemorrhage	J:111325
Rel^tm1Grd/Rel^tm1Grd Rela^tm1Bal/Rela^tm1Bal Tnf^tm1Ljo/Tnf^tm1Ljo involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJae	abnormal cell cycle	J:91366
	abnormal epidermal layer morphology	J:91366
	abnormal epidermis stratum basale morphology	J:91366
	abnormal hair follicle placode formation	J:91366
	abnormal keratinocyte morphology	J:91366
	decreased cell proliferation	J:91366
	decreased embryo size	J:91366
	decreased hair follicle number	J:91366
	neonatal lethality, complete penetrance	J:91366
	thin epidermis	J:91366
	underdeveloped hair follicles	J:91366

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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