39 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pfn1tm1a(EUCOMM)Wtsi/Pfn1+ B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi	abnormal cornea morphology	J:211773
	cornea opacity	J:211773
	decreased body weight	J:175295
	decreased bone mineral content	J:175295
	decreased circulating fructosamine level	J:175295
	decreased total body fat amount	J:175295
	fused cornea and lens	J:211773
	improved glucose tolerance	J:211773
	increased circulating amylase level	J:211773
	increased circulating magnesium level	J:211773
Pfn1tm1a(EUCOMM)Wtsi/Pfn1tm1a(EUCOMM)Wtsi B6Brd;B6Dnk;B6N-Tyrc-Brd Pfn1tm1a(EUCOMM)Wtsi/Wtsi	preweaning lethality, complete penetrance	J:211773
Pfn1tm1Fgi/Pfn1+ involves: 129P2/OlaHsd	abnormal cell morphology	J:335495
	abnormal cell nucleus morphology	J:335495
	abnormal mitotic cytokinesis	J:335495
	binucleate	J:335495
	increased cell nucleus count	J:335495
Pfn1tm1Foxp/Pfn1tm1Foxp involves: C57BL/6NTac	no abnormal phenotype detected	J:193938
Pfn1tm1Foxp/Pfn1tm1Foxp Tg(Cdh5-cre/ERT2)1Rha/0 involves: C57BL/6NTac	decreased angiogenesis	J:193938
Pfn1tm1Foxp/Pfn1tm1Foxp Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * C57BL/6NTac * SJL	abnormal vascular endothelial cell migration	J:193938
	abnormal vascular wound healing	J:193938
	decreased angiogenesis	J:193938
	delayed wound healing	J:193938
Pfn1tm1Ref/Pfn1tm1Ref Tg(Col2a1-cre)1Asz/0 involves: 129T2/SvEms * C57BL/6 * CBA	abnormal chondrocyte differentiation	J:148004
	abnormal chondrocyte physiology	J:148004
	abnormal long bone epiphyseal plate proliferative zone	J:148004
	abnormal long bone hypertrophic chondrocyte zone	J:148004
	abnormal skeleton development	J:148004
	decreased body length	J:148004
	decreased body size	J:148004
	decreased body weight	J:148004
	decreased length of long bones	J:148004
	decreased survivor rate	J:148004
	increased width of hypertrophic chondrocyte zone	J:148004
	kyphoscoliosis	J:148004
	postnatal lethality, incomplete penetrance	J:148004
	short femur	J:148004
	short humerus	J:148004
	weakness	J:148004
Pfn1tm1Wit/Pfn1+ B6.129S4-Pfn1tm1Wit	perinatal lethality, incomplete penetrance	J:77643
	prenatal lethality, incomplete penetrance	J:77643
Pfn1tm1Wit/Pfn1+ involves: 129S4/SvJae * BALB/c	perinatal lethality, incomplete penetrance	J:77643
	prenatal lethality, incomplete penetrance	J:77643
Pfn1tm1Wit/Pfn1+ involves: 129S4/SvJae * C57BL/6	perinatal lethality, incomplete penetrance	J:77643
	prenatal lethality, incomplete penetrance	J:77643
Pfn1tm1Wit/Pfn1tm1Wit B6.129S4-Pfn1tm1Wit	embryonic lethality before implantation, complete penetrance	J:77643
Pfn1tm1Wit/Pfn1tm1Wit involves: 129S4/SvJae * BALB/c	embryonic lethality before implantation, complete penetrance	J:77643
Pfn1tm1Wit/Pfn1tm1Wit involves: 129S4/SvJae * C57BL/6	embryonic lethality before implantation, complete penetrance	J:77643