About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pappa
pregnancy-associated plasma protein A
MGI:97479
23 phenotypes from 6 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Pappam1Btlr/Pappam1Btlr
C57BL/6J-Pappam1Btlr 		decreased body weight J:272859
decreased bone mineral content J:272859
decreased bone mineral density J:272859
decreased bone mineral density of femur J:272859
decreased lean body mass J:272859
Pappam1Btlr/Pappam1Btlr
C57BL/6J-Pappam1Btlr/Btlr 		decreased bone mineral density J:309727
decreased bone mineral density of femur J:309727
short tibia J:309727
small pubis J:309727
PappaM2Btlr/PappaM2Btlr
C57BL/6J-PappaM2Btlr 		decreased body weight J:272860
Pappam3Btlr/Pappam3Btlr
C57BL/6J-Pappam3Btlr 		decreased body weight J:272861
Pappam4Btlr/Pappam4Btlr
C57BL/6J-Pappam4Btlr 		decreased body weight J:274970
Pappatm1Cac/Pappatm1Cac
involves: 129 * C57BL/6 		abnormal enzyme/coenzyme activity J:161983
abnormal enzyme/coenzyme level J:161983
decreased birth body size J:88578
decreased body length J:88578
decreased body weight J:88578, J:161983
decreased circulating estradiol level J:161983
decreased circulating progesterone level J:161983
decreased litter size J:161983
decreased ovary weight J:161983
decreased superovulation rate J:161983
delayed bone ossification J:88578
increased circulating estradiol level J:161983
proportional dwarf J:88578
reduced female fertility J:161983
small ovary J:161983
Pappatm1Lex/Pappatm1Lex
involves: 129S5/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:201775
Pappatm1Lex/Pappatm1Lex
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S5/SvEvBrd * C57BL/6 * CBA 		abnormal vascular wound healing J:201775
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory