Ntrk1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
MGI:97383

22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bax^tm1Sjk/Bax^tm1Sjk Ntrk1^tm1Apat/Ntrk1^tm1Apat involves: 129S1/Sv * 129X1/SvJ	abnormal neuron morphology	J:154926
Bax^tm1Sjk/Bax^tm1Sjk Ntrk1^{tm2(Ntrk3)Apat}/Ntrk1^{tm2(Ntrk3)Apat} involves: 129S1/Sv * 129X1/SvJ	abnormal proprioceptive neuron morphology	J:92099
	increased muscle spindle number	J:92099
Ntf5^tm1Par/Ntf5^tm1Par Ntrk1^tm1Par/Ntrk1^tm1Par involves: 129S1/Sv * C57BL/6	small dorsal root ganglion	J:60927
Ntrk1^{tm1.1(NTRK1)Cat}/Ntrk1⁺ involves: 129S1/Sv 129X1/SvJ * BALB/cJ	abnormal dorsal root ganglion morphology	J:370501
	abnormal skin sensory neuron innervation pattern	J:370501
	anhidrosis	J:370501
	decreased anxiety-related response	J:370501
	decreased social investigation	J:370501
	decreased social novelty preference	J:370501
	hypoalgesia	J:370501
	impaired spatial working memory	J:370501
	increased chemical nociceptive threshold	J:370501
	increased mechanical nociceptive threshold	J:370501
	increased thermal nociceptive threshold	J:370501
Ntrk1^{tm1.1(NTRK1)Cat}/Ntrk1^{tm1.1(NTRK1)Cat} involves: 129S1/Sv * 129X1/SvJ * BALB/cJ	postnatal lethality, complete penetrance	J:370501
	slow postnatal weight gain	J:370501
Ntrk1^{tm2(Ntrk3)Apat}/Ntrk1^{tm2(Ntrk3)Apat} involves: 129S1/Sv	abnormal pain threshold	J:92099
	abnormal proprioceptive neuron morphology	J:92099
	decreased sensory neuron number	J:92099
	increased muscle spindle number	J:92099
	premature death	J:92099
Ntrk1^{tm2(Ntrk3)Apat}/Ntrk1^{tm2(Ntrk3)Apat} Ntrk3^tm1Bbd/Ntrk3^tm1Bbd involves: 129S1/Sv	absent proprioceptive neurons	J:92099
Ntrk1^{tm2(Ntrk3)Apat}/Ntrk1^{tm2(Ntrk3)Apat} Tg(Myog-Ntf3)5160Wds/0 involves: 129S1/Sv	abnormal proprioceptive neuron morphology	J:92099
Ntrk1^{tm2.1(NTRK1)Cat}/Ntrk1⁺ involves: 129S1/Sv * 129X1/SvJ * BALB/cJ	normal behavior/neurological phenotype	J:370501

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/29/2025 MGI 6.24