123 phenotypes from 5 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nos1tm1(cre)Mgmj/Nos1+ B6.129-Nos1tm1(cre)Mgmj	no abnormal phenotype detected	J:179120
Nos1tm1.1(cre/ERT2)Zjh/Nos1+ involves: 129S4/SvJae * C57BL/6 * SJL	no abnormal phenotype detected	J:151755
Nos1tm1Enik/Nos1tm1Enik involves: 129X1/SvJ * C57BL/6	abnormal neuron differentiation	J:99879
Nos1tm1Plh/Nos1+ B6.129S4-Nos1tm1Plh	abnormal cardiovascular system physiology	J:105579
	abnormal heart rate	J:105579
	abnormal physiological response to xenobiotic	J:105579
Nos1tm1Plh/Nos1tm1Plh B6.129S4-Nos1tm1Plh	abnormal blood-brain barrier function	J:150557
	abnormal maternal behavior	J:57543
	abnormal nervous system physiology	J:107964
	abnormal seizure response to inducing agent	J:107964
	abnormal serotonin level	J:127032
	normal behavior/neurological phenotype	J:67776
	normal cardiovascular system phenotype	J:106207
	decreased adiponectin level	J:155090
	decreased aggression towards male mice	J:57543
	decreased cerebral infarct size	J:128835
	decreased susceptibility to induced choroidal neovascularization	J:106207
	decreased susceptibility to ischemic brain injury	J:128835
	decreased susceptibility to neuronal excitotoxicity	J:150557
	increased aggression towards male mice	J:127032
	increased circulating triglyceride level	J:155090
	maternal effect	J:57543
Nos1tm1Plh/Nos1tm1Plh B6.129S4-Nos1tm1Plh/J	decreased body weight	J:144588
	decreased inflammatory response	J:103018
	decreased skeletal muscle weight	J:144588
	impaired skeletal muscle contractility	J:144588
	increased muscle fatigability	J:144588
Nos1tm1Plh/Nos1tm1Plh B6;129S4-Nos1tm1Plh/J	abnormal brain wave pattern	J:83571
	abnormal osteoclast differentiation	J:105612
	abnormal skeleton development	J:105612
	abnormal sleep pattern	J:83571
	abnormal trabecular bone morphology	J:105612
	normal behavior/neurological phenotype	J:83571
	increased bone mineral content	J:105612
	increased bone mineral density	J:105612
	increased trabecular bone thickness	J:105612
	increased trabecular bone volume	J:105612
Nos1tm1Plh/Nos1tm1Plh involves: 129S4/SvJae	abnormal cerebral blood flow rate	J:84255
	abnormal gastroesophageal sphincter physiology	J:56948, J:70182
	abnormal leukocyte adhesion	J:55936
	abnormal long-term potentiation	J:19282
	abnormal muscle physiology	J:89581
	abnormal muscle relaxation	J:56948, J:89581
	abnormal nervous system physiology	J:93439
	abnormal neutrophil physiology	J:55936
	abnormal response of heart to induced stress	J:60525
	abnormal vascular wound healing	J:120009
	absent long-term depression	J:42548
	normal behavior/neurological phenotype	J:42548, J:56005
	normal cardiovascular system phenotype	J:57624
	decreased body weight	J:60525
	decreased cerebral infarct size	J:127062
	decreased coronary flow rate	J:60525
	decreased heart weight	J:60525
	decreased survivor rate	J:100308
	decreased susceptibility to injury	J:93439
	decreased susceptibility to neuronal excitotoxicity	J:111644
	decreased synaptic glutamate release	J:119052
	enhanced leukocyte tethering or rolling	J:55936
	impaired balance	J:56005
	insulin resistance	J:62229
	normal nervous system phenotype	J:37956, J:84255
	premature death	J:100308
	normal reproductive system phenotype	J:89704
	normal vision/eye phenotype	J:56005
Nos1tm1Plh/Nos1tm1Plh involves: 129S4/SvJae * C57BL/6	abnormal brain morphology	J:104558
	abnormal breathing pattern	J:106328
	abnormal carbon dioxide production	J:106328
	abnormal cardiac muscle relaxation	J:103346
	abnormal dendrite morphology	J:111340
	abnormal hepatocyte morphology	J:133437
	abnormal liver morphology	J:104558, J:133437
	abnormal mating frequency	J:29970
	abnormal mitochondrial physiology	J:104558
	abnormal motor neuron morphology	J:111340
	abnormal muscle physiology	J:104916
	abnormal oxygen consumption	J:106328
	abnormal peripheral nervous system regeneration	J:104916
	abnormal pulmonary respiratory rate response	J:106328
	abnormal renal tubule morphology	J:104558
	abnormal stomach wall morphology	J:16390
	decreased cardiac muscle contractility	J:75645
	decreased ovulation rate	J:89701
	decreased superovulation rate	J:89701
	decreased survivor rate	J:129064
	decreased susceptibility to induced morbidity/mortality	J:106328
	delayed peripheral nervous system regeneration	J:104916
	enlarged stomach	J:16390
	normal growth/size/body region phenotype	J:133437
	heart left ventricle hypertrophy	J:75645
	normal homeostasis/metabolism phenotype	J:29970
	increased aggression towards female mice	J:29970
	increased aggression towards male mice	J:29970
	increased oxygen consumption	J:106328
	increased physiological sensitivity to xenobiotic	J:106328
	increased pulmonary respiratory rate	J:106328
	increased pulmonary ventilation	J:106328
	increased tidal volume	J:106328
	increased ventricle muscle contractility	J:103346
	normal nervous system phenotype	J:16390
	premature death	J:16390, J:129064
	pyloric sphincter hypertrophy	J:16390
	pyloric stenosis	J:16390
	slow Wallerian degeneration	J:104916
	stomach smooth muscle circular layer hypertrophy	J:16390
Nos1tm1Plh/Nos1tm1Plh involves: 129S4/SvJae * C57BL/6J	abnormal behavioral response to addictive substance	J:79215
	abnormal digestion	J:64225
	abnormal liquid preference	J:79215
	abnormal renal reabsorption	J:64896
	abnormal renal water reabsorption	J:64896
	abnormal spatial learning	J:101815
	decreased mean systemic arterial blood pressure	J:64896
	normal digestive/alimentary phenotype	J:64225
	enhanced behavioral response to addictive substance	J:79215
	enhanced coordination	J:101815
	enlarged duodenum	J:64225
	enlarged esophagus	J:64225
	enlarged stomach	J:64225
	gastric hypertrophy	J:64225
	normal homeostasis/metabolism phenotype	J:79215
	impaired gastric peristalsis	J:64225
	increased aggression towards male mice	J:67776
	increased alcohol consumption	J:79215
	increased anxiety-related response	J:101815
	increased coping response	J:101815
	increased grooming behavior	J:101815
	increased heart rate	J:108674
	increased urine bicarbonate level	J:64896
	increased urine pH	J:64896
	metabolic acidosis	J:64896
	pyloric sphincter hypertrophy	J:64225
Nos1tm1Plh/Nos1tm1Plh involves: 129S4/SvJae * C57BL/10ScSn	normal muscle phenotype	J:48851
Nos1tm2Plh/Nos1tm2Plh Not Specified	abnormal hypothalamus secretion	J:106816
	abnormal mating frequency	J:106816
	decreased body weight	J:106816
	decreased circulating follicle stimulating hormone level	J:106816
	decreased corpora lutea number	J:106816
	decreased ovary weight	J:106816
	decreased testis weight	J:106816
	enlarged stomach	J:106816
	increased circulating luteinizing hormone level	J:106816
	male infertility	J:106816
	pyloric stenosis	J:106816
	reduced female fertility	J:106816