Ncam1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ncam1
neural cell adhesion molecule 1
MGI:97281

29 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ncam1^tm1.1Mag/Ncam1^tm1.1Mag involves: 129S2/SvPas * C3H * CF-1	normal behavior/neurological phenotype	J:96708
Ncam1^tm1Cgn/Ncam1^tm1Cgn B6.129P2-Ncam1^tm1Cgn	abnormal CNS glial cell morphology	J:126687
Ncam1^tm1Cgn/Ncam1^tm1Cgn B6.129P2-Ncam1^tm1Cgn	abnormal neuron differentiation	J:126687
Ncam1^tm1Cgn/Ncam1^tm1Cgn involves: 129P2/OlaHsd	abnormal spatial learning	J:16590
	decreased brain size	J:16590
	small olfactory bulb	J:16590
Ncam1^tm1Cgn/Ncam1^tm1Cgn involves: 129P2/OlaHsd * C57BL/6J	abnormal rod electrophysiology	J:235028
	abnormal total retina thickness	J:235028
	abnormal vision	J:235028
	decreased retina ganglion cell number	J:235028
	decreased visual acuity	J:235028
	increased retina ganglion cell number	J:235028
	thick retina ganglion layer	J:235028
	thick retina inner plexiform layer	J:235028
	thin retina inner nuclear layer	J:235028
	thin retina outer nuclear layer	J:235028
	thin retina outer plexiform layer	J:235028
Ncam1^tm1Cgn/Ncam1^tm1Cgn involves: C57BL/6J	abnormal circadian behavior period	J:96708
	abnormal circadian behavior phase	J:96708
	shortened circadian behavior period	J:96708
Ncam1^tm1Klc/Ncam1⁺ either: (involves: 129 * C57BL/6J) or (involves: 129 * CD-1)	abnormal hippocampus CA3 region morphology	J:46176
Ncam1^tm1Klc/Ncam1^tm1Klc either: (involves: 129 * C57BL/6J) or (involves: 129 * CD-1)	abnormal hippocampus CA3 region morphology	J:46176
	abnormal postnatal subventricular zone morphology	J:46176
	small olfactory bulb	J:46176
Ncam1^tm1Mag/Ncam1^tm1Mag involves: 129S2/SvPas * CF-1	abnormal cerebellum morphology	J:37891
	abnormal hippocampus pyramidal cell layer	J:37891
	abnormal olfactory bulb morphology	J:37891
	abnormal retina morphology	J:37891
	shortened circadian behavior period	J:96708
	small olfactory bulb	J:37891
Ncam1^tm1Msch/Ncam1^tm1Msch Tg(Camk2a-cre)1Gsc/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	absent long-term depression	J:96990
	normal behavior/neurological phenotype	J:96990
	reduced long-term potentiation	J:96990
Ncam1^tm2Mag/Ncam1⁺ involves: 129 * C57BL/6	prenatal lethality, complete penetrance	J:34293

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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