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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Lifr
LIF receptor alpha
MGI:96788
32 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Lifrtm1b(EUCOMM)Hmgu/Lifr+
C57BL/6N-Lifrtm1b(EUCOMM)Hmgu/H
abnormal brain morphology J:211773
Lifrtm1b(EUCOMM)Hmgu/Lifrtm1b(EUCOMM)Hmgu
C57BL/6N-Lifrtm1b(EUCOMM)Hmgu/H
preweaning lethality, complete penetrance J:211773
Lifrtm1Cgre/Lifrtm1Cgre
either: (involves: 129P2/OlaHsd * CBA) or (involves: 129P2/OlaHsd * MF1)
decreased body weight J:82048
decreased motor neuron number J:82048
neonatal lethality, complete penetrance J:82048
Lifrtm1Imx/Lifr+
B6;129S7-Lifrtm1Imx/J
abnormal ureter morphology J:242320
cryptorchism J:242320
hydroureter J:242320
Lifrtm1Imx/Lifrtm1Imx
B6;129S7-Lifrtm1Imx/J
abnormal kidney development J:242320
abnormal kidney morphology J:242320
abnormal renal/urinary system morphology J:242320
abnormal ureter morphology J:242320
abnormal ureter smooth muscle morphology J:242320
blind ureter J:242320
cryptorchism J:242320
decreased fetal size J:242320
decreased nephron number J:242320
decreased renal glomerulus number J:242320
ectopic ureter J:242320
hydronephrosis J:242320
hydroureter J:242320
prenatal lethality, incomplete penetrance J:242320
renal hypoplasia J:242320
small kidney J:242320
Lifrtm1Imx/Lifrtm1Imx
involves: 129P3/J * 129S7/SvEvBrd * C57BL/6
abnormal astrocyte morphology J:25253
abnormal dorsal root ganglion morphology J:25253
abnormal long bone morphology J:25253
abnormal metacarpal bone morphology J:25253
abnormal placenta morphology J:25253
decreased body size J:25253
decreased bone mineral density J:25253
decreased bone volume J:25253
embryonic lethality before implantation, incomplete penetrance J:25253
increased liver glycogen level J:25253
increased osteoclast cell number J:25253
neonatal lethality, complete penetrance J:25253

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory