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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Jup
junction plakoglobin
MGI:96650
91 phenotypes from 10 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Juptm1.1(KOMP)Vlcg/Jup+
C57BL/6N-Juptm1.1(KOMP)Vlcg/J
abnormal embryo size J:211773
decreased coping response J:211773
decreased fasting circulating glucose level J:211773
increased hemoglobin content J:211773
Juptm1.1(KOMP)Vlcg/Juptm1.1(KOMP)Vlcg
C57BL/6N-Juptm1.1(KOMP)Vlcg/J
abnormal embryo size J:211773
prenatal lethality J:211773
preweaning lethality, complete penetrance J:211773
Juptm1.1Chen/Juptm1.1Chen
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
abnormal skin physiology J:222025
normal cardiovascular system phenotype J:222025
loose skin J:222025
neonatal lethality, complete penetrance J:222025
thin epidermis J:222025
wrinkled skin J:222025
Juptm1.1Glr/Juptm1.1Glr
A1cfTg(Myh6-cre/Esr1*)1Jmk/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL
abnormal cardiovascular system physiology J:170618
abnormal heart right ventricle morphology J:170618
abnormal intercalated disk morphology J:170618
abnormal interleukin level J:170618
abnormal myocardial fiber morphology J:170618
abnormal sarcomere morphology J:170618
cardiac fibrosis J:170618
normal cardiovascular system phenotype J:170618
decreased ventricle muscle contractility J:170618
diffuse Z line J:170618
dilated heart left ventricle J:170618
enlarged myocardial fiber J:170618
heart inflammation J:170618
heart left ventricle hypertrophy J:170618
increased heart left ventricle size J:170618
increased heart right ventricle size J:170618
increased heart weight J:170618
premature death J:170618
pulmonary edema J:170618
Juptm1.1Shou/Juptm1.1Shou
Tg(Myh6-cre)2182Mds/0
involves: 129 * C57BL/6J
abnormal cardiovascular system physiology J:177567
abnormal heart electrocardiography waveform feature J:177567
abnormal heart ventricle morphology J:177567
abnormal impulse conducting system conduction J:177567
abnormal myocardial fiber morphology J:177567
abnormal P wave J:177567
calcified myocardium J:177567
cardiac fibrosis J:177567
cardiac muscle necrosis J:177567
cardiomyopathy J:177567
decreased cardiac muscle contractility J:177567
decreased QRS amplitude J:177567
dilated heart J:177567
dilated heart right ventricle J:177567
enlarged heart J:177567
enlarged heart right atrium J:177567
increased cardiomyocyte apoptosis J:177567
liver vascular congestion J:177567
premature death J:177567
prolonged PR interval J:177567
ventricular aneurysm J:177567
ventricular tachycardia J:177567
Juptm1.2Glr/Juptm1.2Glr
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * SJL
embryonic lethality J:170618
Juptm1Kem/Juptm1Kem
involves: 129S1/Sv * 129X1/SvJ
abnormal atrioventricular cushion morphology J:38047
abnormal blood circulation J:38047
abnormal heart atrium morphology J:38047
abnormal heart development J:38047
absent cardiac desmosomes J:38047
embryonic lethality during organogenesis, incomplete penetrance J:38047
hemopericardium J:38047
small liver J:38047
small placenta J:38047
thin myocardium J:38047
trabecula carnea hypoplasia J:38047
Juptm1Kem/Juptm1Kem
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal atrial thrombosis J:38047
abnormal atrioventricular cushion morphology J:38047
abnormal epidermal layer morphology J:38047
abnormal epidermis stratum granulosum morphology J:38047
abnormal epidermis stratum spinosum morphology J:38047
abnormal heart atrium morphology J:38047
abnormal heart development J:38047
abnormal thrombosis J:38047
absent cardiac desmosomes J:38047
absent epidermis stratum corneum J:38047
acantholysis J:38047
blistering J:38047
decreased skin tensile strength J:38047
embryonic lethality during organogenesis, incomplete penetrance J:38047
enlarged heart J:38047
hemopericardium J:38047
impaired skin barrier function J:38047
normal integument phenotype J:38047
small liver J:38047
small placenta J:38047
thin epidermis J:38047
thin myocardium J:38047
trabecula carnea hypoplasia J:38047
Juptm1Ruiz/Jup+
involves: 129P2/OlaHsd * C57BL/6
abnormal fat cell differentiation J:192719
abnormal heart echocardiography feature J:192719
thin interventricular septum J:192719
Juptm1Ruiz/Jup+
Tg(Myh6-Jup*)1Ajm/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
abnormal cardiovascular system morphology J:192719
abnormal fat cell morphology J:192719
abnormal heart echocardiography feature J:192719
abnormal heart morphology J:192719
decreased ventricle muscle contractility J:192719
thin interventricular septum J:192719
Juptm1Ruiz/Juptm1Ruiz
involves: 129P2/OlaHsd
abnormal heart development J:178688
embryonic lethality during organogenesis, incomplete penetrance J:178688
lethality throughout fetal growth and development, complete penetrance J:178688
Juptm1Ruiz/Juptm1Ruiz
involves: 129P2/OlaHsd * C57BL/6
abnormal blood circulation J:64280
abnormal cardiac muscle contractility J:64280
abnormal heart morphology J:64280
abnormal intercalated disk morphology J:64280
abnormal liver morphology J:64280
abnormal spongiotrophoblast layer morphology J:64280
absent cardiac desmosomes J:64280
decreased spongiotrophoblast size J:64280
embryonic growth retardation J:64280
hemopericardium J:64280
increased heart rate J:64280
lethality throughout fetal growth and development, complete penetrance J:64280
pallor J:64280
Juptm1Ruiz/Juptm1Ruiz
Tg(Myh6-Jup*)1Ajm/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
prenatal lethality, complete penetrance J:192719
Juptm2.1Chen/Juptm2.1Chen
involves: 129S1/Sv * 129X1/SvJ
no abnormal phenotype detected J:222025
Tg(Myh6-Jup)2Ajm/0
involves: FVB/N
abnormal fat cell morphology J:192719
abnormal heart echocardiography feature J:192719
abnormal heart morphology J:192719
cardiac interstitial fibrosis J:192719
premature death J:192719
Tg(Myh6-Jup*)1Ajm/0
involves: FVB/N
abnormal fat cell differentiation J:192719
abnormal fat cell morphology J:192719
abnormal heart echocardiography feature J:192719
abnormal heart morphology J:192719
abnormal heart weight J:192719
atrioventricular block J:192719
cardiac interstitial fibrosis J:192719
decreased ventricle muscle contractility J:192719
enlarged heart J:192719
irregular heartbeat J:192719
premature death J:192719
ventricular tachycardia J:192719

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory