Il6sttm1.1Wme/Il6sttm1.1Wme
involves: 129P2/OlaHsd * C57BL/6
|
abnormal embryonic growth/weight/body size |
J:67677
|
|
decreased embryo size |
J:67677
|
|
normal
growth/size/body region phenotype |
J:67677
|
|
lethality during fetal growth through weaning, complete penetrance |
J:67677
|
Il6sttm1Ard/Il6sttm1Ard
involves: 129S1/Sv * C57BL/6
|
abnormal common myeloid progenitor cell morphology |
J:110742
|
|
abnormal digestive system morphology |
J:79555
|
|
abnormal femur morphology |
J:87612
|
|
abnormal involution of the mammary gland |
J:93986
|
|
abnormal joint morphology |
J:79555
|
|
abnormal leukocyte cell number |
J:110742
|
|
abnormal megakaryocyte morphology |
J:110742
|
|
abnormal synovial joint capsule morphology |
J:79555
|
|
abnormal thrombopoiesis |
J:110742
|
|
cecum inflammation |
J:79555
|
|
conjunctivitis |
J:79555
|
|
decreased body length |
J:79555
|
|
decreased body weight |
J:79555
|
|
decreased diameter of femur |
J:87612
|
|
decreased IgA level |
J:79555
|
|
decreased IgG level |
J:79555
|
|
decreased immunoglobulin level |
J:79555
|
|
decreased joint mobility |
J:79555
|
|
decreased megakaryocyte cell number |
J:110742
|
|
failure of embryo implantation |
J:79555
|
|
female infertility |
J:79555
|
|
gastric ulcer |
J:79555
|
|
gastrointestinal hemorrhage |
J:79555
|
|
gastrointestinal ulcer |
J:79555
|
|
increased cell proliferation |
J:79555
|
|
increased inflammatory response |
J:79555
|
|
increased megakaryocyte cell number |
J:110742
|
|
increased physiological sensitivity to xenobiotic |
J:79073
|
|
increased susceptibility to induced colitis |
J:79073
|
|
increased susceptibility to parasitic infection |
J:79555
|
|
increased susceptibility to xenobiotic induced morbidity/mortality |
J:79073
|
|
joint swelling |
J:79555
|
|
postnatal lethality, incomplete penetrance |
J:79555
|
|
premature death |
J:79555
|
|
rectal prolapse |
J:79555
|
|
short femur |
J:87612
|
|
normal
skeleton phenotype |
J:87612
|
|
thrombocytopenia |
J:110742
|
Il6sttm1Ard/Il6sttm1Wme
Tg(Alb1-cre)7Gsc/?
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * FVB/N
|
abnormal liver physiology |
J:97327
|
|
abnormal liver regeneration |
J:135290
|
|
increased susceptibility to induced morbidity/mortality |
J:97327
|
Il6sttm1b(KOMP)Mbp/Il6st+
C57BL/6N-Il6sttm1b(KOMP)Mbp/J
|
increased circulating bilirubin level |
J:211773
|
|
increased mean corpuscular hemoglobin concentration |
J:211773
|
Il6sttm1b(KOMP)Mbp/Il6sttm1b(KOMP)Mbp
C57BL/6N-Il6sttm1b(KOMP)Mbp/J
|
embryonic lethality prior to tooth bud stage |
J:211773
|
|
preweaning lethality, complete penetrance |
J:211773
|
Il6sttm1Ern/Il6sttm1Ern
involves: 129S1/Sv
|
increased circulating interleukin-6 level |
J:168781
|
|
increased interleukin-6 secretion |
J:168781
|
|
increased neutrophil cell number |
J:168781
|
|
increased susceptibility to endotoxin shock |
J:168781
|
|
increased susceptibility to xenobiotic induced morbidity/mortality |
J:168781
|
Il6sttm1Ern/Il6sttm1Ern
involves: 129S1/Sv * C57BL/6
|
abnormal digestive system physiology |
J:87206
|
|
abnormal inflammatory response |
J:139226
|
|
abnormal small intestine morphology |
J:79073
|
|
abnormal stomach morphology |
J:79073
|
|
abnormal stomach mucosa morphology |
J:79073,
J:87206
|
|
abnormal trabecular bone morphology |
J:87612
|
|
decreased compact bone thickness |
J:87612
|
|
decreased physiological sensitivity to xenobiotic |
J:79073
|
|
decreased susceptibility to induced colitis |
J:79073
|
|
decreased trabecular bone thickness |
J:87612
|
|
enlarged spleen |
J:79073
|
|
enlarged stomach |
J:79073
|
|
increased adenoma incidence |
J:79073,
J:87206
|
|
increased osteoblast cell number |
J:87612
|
|
increased osteoclast cell number |
J:87612
|
|
increased stomach pH |
J:87206
|
|
increased susceptibility to induced arthritis |
J:142883
|
|
stomach inflammation |
J:87206
|
Il6sttm1Ern/Il6sttm1Wme
Tg(Alb1-cre)7Gsc/?
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * FVB/N
|
abnormal liver regeneration |
J:135290
|
|
normal
liver/biliary system phenotype |
J:97327
|
Il6sttm1Kish/Il6sttm1Kish
involves: 129P2/OlaHsd * C57BL/6
|
anemia |
J:75419
|
|
decreased common myeloid progenitor cell number |
J:75419
|
|
decreased embryo size |
J:75419
|
|
decreased erythroid progenitor cell number |
J:75419
|
|
decreased hematopoietic stem cell number |
J:75419
|
|
increased nucleated erythrocyte cell number |
J:75419
|
|
lethality throughout fetal growth and development, complete penetrance |
J:75419
|
|
thin ventricular wall |
J:75419
|
|
thymus hypoplasia |
J:75419
|
Il6sttm1Kish/Il6sttm1Kish
involves: 129P2/OlaHsd * CD-1
|
abnormal bone marrow development |
J:88710
|
|
abnormal long bone diaphysis morphology |
J:88710
|
|
abnormal long bone morphology |
J:88710
|
|
abnormal osteoblast physiology |
J:88710
|
|
abnormal osteoclast differentiation |
J:88710
|
|
abnormal osteoclast morphology |
J:88710
|
|
abnormal osteoclast physiology |
J:88710
|
|
abnormal skeleton morphology |
J:88710
|
|
abnormal trabecular bone morphology |
J:88710
|
|
bowed femur |
J:88710
|
|
bowed fibula |
J:88710
|
|
bowed humerus |
J:88710
|
|
bowed radius |
J:88710
|
|
bowed tibia |
J:88710
|
|
bowed ulna |
J:88710
|
|
decreased body size |
J:88710
|
|
decreased circulating calcium level |
J:88710
|
|
decreased osteoblast cell number |
J:88710
|
|
increased activity of parathyroid |
J:88710
|
|
increased circulating parathyroid hormone level |
J:88710
|
|
increased osteoclast cell number |
J:88710
|
|
neonatal lethality, complete penetrance |
J:88710
|
|
short limbs |
J:88710
|
Il6sttm1Kish/Il6sttm1Kish
involves: 129P2/OlaHsd * ICR
|
abnormal cortical plate morphology |
J:124527
|
|
decreased liver glycogen level |
J:54660
|
|
postnatal lethality |
J:54660
|
Il6sttm1Mam/Il6sttm1Mam
Tg(Wap-cre)11738Mam/0
Not Specified
|
abnormal involution of the mammary gland |
J:93986
|
Il6sttm1Thir/Il6sttm1Thir
B6.Cg-Il6sttm1Thir
|
abnormal bone structure |
J:144906
|
|
abnormal osteoblast physiology |
J:144906
|
|
increased bone mineral content |
J:144906
|
|
increased bone mineral density |
J:144906
|
|
increased bone mineralization |
J:144906
|
|
increased bone ossification |
J:144906
|
|
increased trabecular bone thickness |
J:144906
|
Il6sttm1Thir/Il6sttm1Thir
involves: 129 * C57BL/6
|
abnormal T cell activation |
J:133059
|
|
abnormal T cell clonal deletion |
J:133059
|
|
abnormal thymocyte activation |
J:133059
|
|
decreased double-positive T cell number |
J:133059
|
|
increased activated T cell number |
J:133059
|
|
increased anti-double stranded DNA antibody level |
J:133059
|
|
increased anti-nuclear antigen antibody level |
J:133059
|
|
increased anti-single stranded DNA antibody level |
J:133059
|
|
increased autoantibody level |
J:133059
|
|
increased double-negative T cell number |
J:133059
|
|
increased IgA level |
J:133059
|
|
increased IgG1 level |
J:133059
|
|
increased IgG2a level |
J:133059
|
|
increased IgG2b level |
J:133059
|
|
increased neutrophil cell number |
J:133059
|
|
increased single-positive T cell number |
J:133059
|
|
osteoporosis |
J:133059
|
|
rheumatoid arthritis |
J:133059
|
Il6sttm1Thir/Il6sttm1Thir
Not Specified
|
abnormal action potential |
J:130276
|
|
abnormal B cell physiology |
J:59922
|
|
abnormal channel response intensity |
J:130276
|
|
abnormal dendritic cell antigen presentation |
J:113335
|
|
abnormal myocardial fiber physiology |
J:130276
|
|
abnormal peritoneum morphology |
J:59922
|
|
decreased interleukin-4 secretion |
J:59922
|
|
enlarged axillary lymph nodes |
J:59922
|
|
enlarged cervical lymph nodes |
J:59922
|
|
enlarged inguinal lymph nodes |
J:59922
|
|
enlarged mesenteric lymph nodes |
J:59922
|
|
increased B cell number |
J:59922
|
|
increased CD4-positive, alpha-beta T cell number |
J:59922
|
|
increased CD8-positive, alpha-beta T cell number |
J:59922
|
|
increased IgG2a level |
J:59922
|
|
increased IgG2b level |
J:59922
|
|
increased interferon-gamma secretion |
J:59922
|
|
lymph node hyperplasia |
J:59922
|
|
spleen hyperplasia |
J:59922
|
Il6sttm1Wme/Il6sttm1Wme
involves: 129P2/OlaHsd * C57BL/6
|
abnormal erythropoiesis |
J:67677
|
|
abnormal heart development |
J:67677
|
|
abnormal heart ventricle morphology |
J:67677
|
|
abnormal immunoglobulin level |
J:67677
|
|
abnormal myelination |
J:67677
|
|
abnormal Schwann cell morphology |
J:67677
|
|
abnormal T cell differentiation |
J:67677
|
|
abnormal thrombopoiesis |
J:67677
|
|
decreased thymocyte number |
J:67677
|
|
increased IgE level |
J:67677
|
|
increased IgG level |
J:67677
|
|
increased leukocyte cell number |
J:67677
|
Il6sttm1Wme/Il6sttm1Wme
Tg(Alb1-cre)7Gsc/0
involves: 129P2/OlaHsd * FVB/N
|
abnormal liver regeneration |
J:135290
|
Il6sttm2Thir/Il6sttm2Thir
B6.Cg-Il6sttm2Thir
|
abnormal osteoblast physiology |
J:144906
|
Il6sttm2Thir/Il6sttm2Thir
Not Specified
|
abnormal bone marrow cell morphology/development |
J:59922
|
|
abnormal dendritic cell antigen presentation |
J:113335
|
|
decreased B-1a cell number |
J:59922
|
|
decreased IgG1 level |
J:59922
|
|
decreased IgG2a level |
J:59922
|
|
decreased IgG2b level |
J:59922
|
|
decreased interferon-gamma secretion |
J:59922
|
|
increased IgM level |
J:59922
|
|
neonatal lethality, complete penetrance |
J:59922
|
Il6sttm3Thir/Il6sttm3Thir
Not Specified
|
abnormal astrocyte morphology |
J:59922
|
|
abnormal bone marrow cell morphology/development |
J:59922
|
|
decreased IgA level |
J:59922
|
|
decreased IgG2a level |
J:59922
|
|
decreased IgG2b level |
J:59922
|
|
embryonic lethality, incomplete penetrance |
J:59922
|
|
neonatal lethality, complete penetrance |
J:59922
|
Excel File
Analysis Tools