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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Il5
interleukin 5
MGI:96557
39 phenotypes from 6 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Il5tm1.1(icre)Lky/Il5+
C57BL/6-Il5tm1.1(icre)Lky
decreased circulating interleukin-5 level J:206097
Il5tm1Anjm/Il5tm1Anjm
involves: 129P2/OlaHsd * C57BL/6
abnormal intestinal goblet cell morphology J:113543
abnormal mast cell morphology J:113543
abnormal mast cell physiology J:113543
altered susceptibility to infection J:113543
decreased eosinophil cell number J:113543
decreased IgE level J:113543
granulomatous inflammation J:113543
increased susceptibility to parasitic infection J:113543
Il5tm1Kopf/Il5tm1Kopf
C57BL/6-Il5tm1Kopf
decreased airway responsiveness J:30641
granulomatous inflammation J:107418
increased interferon-gamma secretion J:107418
increased lymphocyte cell number J:30641
increased neutrophil cell number J:30641
liver fibrosis J:107418
Il5tm1Kopf/Il5tm1Kopf
C57BL/6-Il5tm1Kopf/J
increased eosinophil cell number J:30867
Il5tm1Kopf/Il5tm1Kopf
either: C57BL/6-Il5tm1Kopf or (involves: BALB/c * C57BL/6) or (involves: C57BL/6 * CBA)
abnormal mating receptivity J:65853
enlarged placenta J:65853
increased body weight J:65853
prolonged estrous cycle J:65853
Il5tm1Ktk/Il5+
B6.129S4-Il5tm1Ktk
decreased interleukin-5 secretion J:180790
Il5tm1Ktk/Il5tm1Ktk
B6.129S4-Il5tm1Ktk
abnormal B-1 B cell morphology J:180790
decreased interleukin-5 secretion J:180790
increased metastatic potential J:180790
Il5tm3Anjm/Il5tm3Anjm
involves: 129P2/OlaHsd * C57BL/6
granulomatous inflammation J:113543
Tg(Cd3d-Il5)NJ.1638Nal/?
involves: C57BL/6J * CBA/J
abnormal eosinophil differentiation J:123440
abnormal liver morphology J:123440
abnormal spleen morphology J:123440
abnormal T cell number J:123440
alopecia J:123440
enlarged heart J:123440
enlarged lymph nodes J:123440
erythroblastosis J:123440
increased eosinophil cell number J:123440
increased leukocyte cell number J:123440
increased liver weight J:123440
increased mature B cell number J:123440
increased monocyte cell number J:123440
increased neutrophil cell number J:123440
increased spleen weight J:123440
peritoneal inflammation J:123440
premature death J:123440
rectal prolapse J:123440
spontaneous skin ulceration J:123440

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory