About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
MGI:96273
18 phenotypes from 6 alleles in 8 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Htr1atm1.1(KOMP)Vlcg/Htr1atm1.1(KOMP)Vlcg
C57BL/6N-Htr1atm1.1(KOMP)Vlcg/J
abnormal behavioral response to light J:211773
Htr1atm1Rhn/Htr1a+
involves: 129S1/Sv
increased anxiety-related response J:51280
Htr1atm1Rhn/Htr1atm1Rhn
129S6/SvEvTac-Htr1atm1Rhn
abnormal circulating noradrenaline level J:65662
abnormal serotonin level J:65662, J:70686
increased dopamine level J:65662
normal nervous system phenotype J:65662, J:70686
Htr1atm1Rhn/Htr1atm1Rhn
involves: 129S1/Sv
behavioral despair J:51280
increased anxiety-related response J:51280
Htr1atm1Rhn/Htr1atm1Rhn
involves: 129S/SvEv * 129S1/Sv
abnormal nervous system physiology J:167655
increased anxiety-related response J:167655
Htr1atm1Tct/Htr1a+
involves: 129X1/SvJ * C57BL/6J
behavioral despair J:51565
increased anxiety-related response J:51565
Htr1atm1Tct/Htr1atm1Tct
involves: 129X1/SvJ * C57BL/6J
normal behavior/neurological phenotype J:51565
behavioral despair J:51565
increased anxiety-related response J:51565
increased thigmotaxis J:51565
normal nervous system phenotype J:51565
Htr1atm1Toth/Htr1a+
involves: 129P2/OlaHsd * Black Swiss
increased anxiety-related response J:49752
Htr1atm1Toth/Htr1atm1Toth
involves: 129P2/OlaHsd * Black Swiss
abnormal spatial learning J:66581
decreased paired-pulse facilitation J:61579, J:66581
hyperactivity J:49752
increased anxiety-related response J:49752, J:61579
increased susceptibility to pharmacologically induced seizures J:66581
Htr1atm2Rhn/Htr1a+
involves: BALB/c * C57BL/6
decreased vertical activity J:118885
Htr1atm3.1Rhn/?
Tg(HCRT-tTA)G5Ahky/0
B6.Cg-Htr1atm3.1Rhn Tg(HCRT-tTA)G5Ahky
abnormal sleep pattern J:212974
increased frequency of paradoxical sleep J:212974
increased slow-wave sleep duration J:212974

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory