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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hsf2
heat shock factor 2
MGI:96239
34 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Hsf2tm1b(KOMP)Wtsi/Hsf2tm1b(KOMP)Wtsi
C57BL/6N-Hsf2tm1b(KOMP)Wtsi/J
abnormal retina blood vessel morphology J:211773
decreased circulating glucose level J:211773
increased circulating sodium level J:211773
Hsf2tm1Ijb/Hsf2tm1Ijb
either: (involves: 129S6/SvEvTac * 129X1/SvJ) or (involves: 129S6/SvEvTac * C57BL/6)
no abnormal phenotype detected J:79910
Hsf2tm1Miv/Hsf2tm1Miv
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
abnormal seminiferous tubule morphology J:88035
abnormal spermatogenesis J:83730, J:88035
collapsed brain ventricles J:83730
decreased litter size J:83730
decreased male germ cell number J:88035
decreased testis weight J:88035
dilated lateral ventricle J:83730
dilated third ventricle J:83730
intracerebral hemorrhage J:83730
oligozoospermia J:83730, J:88035
postnatal lethality, incomplete penetrance J:83730
prenatal lethality, incomplete penetrance J:83730
reduced female fertility J:83730
small testis J:83730
Hsf2tm1Mmr/Hsf2tm1Mmr
involves: 129S2/SvPas * C57BL/6
abnormal female germ cell morphology J:76942
abnormal male germ cell apoptosis J:76942
abnormal male meiosis J:76942
abnormal ovarian follicle morphology J:76942
abnormal spermatogenesis J:76942
abnormal synaptonemal complex J:76942
absent corpus luteum J:76942
decreased epididymis weight J:76942
decreased litter size J:76942
decreased mature ovarian follicle number J:76942
decreased oocyte number J:76942
decreased testis weight J:76942
enlarged lateral ventricles J:76942
enlarged third ventricle J:76942
maternal effect J:76942
oligozoospermia J:76942
ovarian follicular cyst J:76942
ovary hemorrhage J:76942
reduced female fertility J:76942
small hippocampus J:76942
small seminiferous tubules J:76942
small testis J:76942

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory