About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hoxb1
homeobox B1
MGI:96182
56 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Hoxa1tm1Ipc/Hoxa1tm1Ipc
Hoxb1tm1Ipc/Hoxb1tm1Ipc
involves: 129S2/SvPas * 129S7/SvEvBrd
abnormal neural crest cell delamination J:71033
abnormal neural crest cell migration J:71033
normal embryo phenotype J:71033
normal muscle phenotype J:124278
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
Hoxb1tm3Mrc/Hoxb1+
involves: 129S1/Sv * 129X1/SvJ
abnormal neural crest cell migration J:41540
abnormal neuron differentiation J:41540
abnormal pharyngeal pouch morphology J:41540
abnormal rhombomere morphology J:41540
absent parathyroid glands J:41540
absent second pharyngeal arch J:41540
small thymus J:41540
Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc
Hoxb1tm3Mrc/Hoxb1tm3Mrc
involves: 129S1/Sv * 129X1/SvJ
abnormal digastric posterior belly morphology J:41540
abnormal neural crest cell migration J:41540
abnormal neuron differentiation J:41540
abnormal rhombomere morphology J:41540
abnormal stylohyoid muscle morphology J:41540
abnormal third pharyngeal pouch morphology J:41540
absent facial muscle J:41540
absent levator labii superioris muscle J:41540
absent orbicularis oculi muscle J:41540
absent parathyroid glands J:41540
absent rhombomere 4 J:41540
absent rhombomere 5 J:41540
absent second pharyngeal arch J:41540
absent second pharyngeal pouch J:41540
absent stapes J:41540
absent zygomaticus muscle J:41540
athymia J:41540
increased hindbrain apoptosis J:41540
pulmonary hypoplasia J:41540
small incus J:41540
small malleus J:41540
Hoxa1tm3.1Mrc/Hoxa1tm4(Hoxb1)Mrc
Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
abnormal blinking J:119279
facial paralysis J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc
Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
abnormal facial nerve morphology J:119279
abnormal reflex J:119279
Hoxa1tm4(Hoxb1)Mrc/Hoxa1tm4(Hoxb1)Mrc
Hoxb1tm8(Hoxa1)Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
no abnormal phenotype detected J:119279
Hoxa1tm5Mrc/Hoxa1+
Hoxb1tm5Mrc/Hoxb1tm5Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal facial nerve morphology J:119279
abnormal reflex J:119279
paralysis J:119279
small facial motor nucleus J:119279
Hoxa1tm5Mrc/Hoxa1tm5Mrc
Hoxb1tm5Mrc/Hoxb1tm5Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
normal nervous system phenotype J:119279
Hoxb1tm1(cre)Og/Hoxb1+
Pbx3tm1Og/Pbx3tm1Og
involves: 129S/SvEv * 129S4/SvJae * C57BL/6
abnormal behavior J:130927
abnormal limb posture J:130927
abnormal locomotor coordination J:130927
abnormal neuron differentiation J:130927
abnormal neuron morphology J:130927
abnormal spinal cord dorsal horn morphology J:130927
bradykinesia J:130927
decreased body size J:130927
decreased neuron number J:130927
decreased thermal nociceptive threshold J:130927
hyporesponsive to tactile stimuli J:130927
impaired coordination J:130927
improved righting response J:130927
increased startle reflex J:130927
limb grasping J:130927
Hoxb1tm1.1Mist/Hoxb1tm1.1Mist
Tg(Hoxb1-cre)r4Mist/0
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1
abnormal brainstem morphology J:197162
abnormal cochlear outer hair cell morphology J:197162
abnormal cochlear VIII nucleus morphology J:197162
abnormal organ of Corti morphology J:197162
abnormal pons morphology J:197162
abnormal susceptibility to hearing loss J:197162
increased or absent threshold for auditory brainstem response J:197162
increased susceptibility to age-related hearing loss J:197162
Hoxb1tm1Mist/Hoxb1tm1Mist
Tg(Hoxb1-cre)r4Mist/0
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * CD-1
abnormal brainstem morphology J:197162
abnormal cochlear outer hair cell morphology J:197162
abnormal cochlear VIII nucleus morphology J:197162
abnormal organ of Corti morphology J:197162
abnormal pons morphology J:197162
increased or absent threshold for auditory brainstem response J:197162
increased susceptibility to age-related hearing loss J:197162

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/21/2020
MGI 6.14
The Jackson Laboratory