Gabra2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gabra2
gamma-aminobutyric acid type A receptor subunit alpha 2
MGI:95614

29 phenotypes from 7 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gabra2^em1(IMPC)H/Gabra2^em1(IMPC)H C57BL/6N-Gabra2^em1(IMPC)H/H	abnormal behavior	J:211773
	cornea opacity	J:211773
	decreased exploration in new environment	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased heart rate	J:211773
	decreased locomotor activity	J:211773
	decreased total body fat amount	J:211773
	hyperactivity	J:211773
	increased anxiety-related response	J:211773
	increased grip strength	J:211773
	increased lean body mass	J:211773
	increased thigmotaxis	J:211773
	limb grasping	J:211773
	prolonged RR interval	J:211773
	trunk curl	J:211773
Gabra2^tm1.1Dias/Gabra2^tm1.1Dias involves: 129S7/SvEvBrd * C57BL/6J	normal homeostasis/metabolism phenotype	J:109259
	impaired behavioral response to xenobiotic	J:108919
Gabra2^tm1.1Geh/Gabra2^tm1.1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal miniature inhibitory postsynaptic currents	J:171967
	enhanced behavioral response to anesthetic	J:171967
	enhanced contextual conditioning behavior	J:171967
	enhanced cued conditioning behavior	J:171967
	postnatal lethality, incomplete penetrance	J:171967
Gabra2^tm1.1Uru/Gabra2^tm1.1Uru 129-Gabra2^tm1.1Uru	abnormal GABA-mediated receptor currents	J:65100
Gabra2^tm1.1Uru/Gabra2^tm1.1Uru 129-Gabra2^tm1.1Uru	impaired behavioral response to xenobiotic	J:65100
Gabra2^tm1Dns/Gabra2^tm1Dns involves: 129S7/SvEvBrd * BALB/cJ * C57BL/6J	abnormal conditioned emotional response	J:140077
	decreased survivor rate	J:140077
	postnatal lethality	J:140077
Gabra2^tm1Uru/Gabra2^tm1Uru Tg(Scn10a-cre)1Rkun/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA/2	decreased chemically-elicited antinociception	J:173378
	decreased physiological sensitivity to xenobiotic	J:173378
Gabra2^tm1Uru/Gabra2^tm2.1Uru Tg(Scn10a-cre)1Rkun/0 involves: C57BL/6 * DBA/2 * SJL	decreased chemically-elicited antinociception	J:173378
	decreased physiological sensitivity to xenobiotic	J:173378
Gabra2^tm2.1Uru/Gabra2^tm2.1Uru Tg(Scn10a-cre)1Rkun/0 involves: C57BL/6 * DBA/2 * SJL	abnormal CNS synaptic transmission	J:173378
	abnormal GABA-mediated receptor currents	J:173378
	decreased chemically-elicited antinociception	J:173378
	decreased physiological sensitivity to xenobiotic	J:173378

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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