37 phenotypes from 10 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gabra1tm1.1Geh/Gabra1+ B6.129(Cg)-Gabra1tm1.1Geh	abnormal miniature inhibitory postsynaptic currents	J:227437
	abnormal spike wave discharge	J:186685, J:227437
	absence seizures	J:186685, J:227437
	decreased miniature inhibitory postsynaptic current amplitude	J:227437
	increased susceptibility to pharmacologically induced seizures	J:227437
	myoclonus	J:227437
	seizures	J:227437
	tonic-clonic seizures	J:227437
Gabra1tm1.1Geh/Gabra1+ D2.129(Cg)-Gabra1tm1.1Geh	abnormal spike wave discharge	J:186685
	absence seizures	J:186685
Gabra1tm1.1Geh/Gabra1tm1.1Geh B6.129(Cg)-Gabra1tm1.1Geh	preweaning lethality, incomplete penetrance	J:186685
	weight loss	J:186685
Gabra1tm1.1Geh/Gabra1tm1.1Geh D2.129(Cg)-Gabra1tm1.1Geh	preweaning lethality, incomplete penetrance	J:186685
	weight loss	J:186685
Gabra1tm1.1Geh/Gabra1tm1.1Geh involves: 129S1/Sv * 129X1/SvJ	abnormal synapse morphology	J:199326
Gabra1tm1.1Geh/Gabra1tm1.1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal hearing/vestibular/ear phenotype	J:112951
Gabra1tm1.1Geh/Gabra1tm1.1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal inhibitory postsynaptic currents	J:70505, J:103381
	decreased physiological sensitivity to xenobiotic	J:103381
Gabra1tm1.1Geh/Gabra1tm1.1Mjga B6J.Cg-Gabra1tm1.1Geh Gabra1tm1.1Mjga	postnatal lethality	J:227437
Gabra1tm1.1Mjga/Gabra1+ B6J.Cg-Gabra1tm1.1Mjga	abnormal miniature inhibitory postsynaptic currents	J:227437
	abnormal spike wave discharge	J:227437
	absence seizures	J:227437
	decreased miniature inhibitory postsynaptic current amplitude	J:227437
	increased susceptibility to pharmacologically induced seizures	J:227437
	myoclonus	J:227437
	seizures	J:227437
	tonic-clonic seizures	J:227437
Gabra1tm1.1Mjga/Gabra1tm1.1Mjga B6J.Cg-Gabra1tm1.1Mjga	postnatal lethality	J:227437
Gabra1tm1.1Uru/Gabra1tm1.1Uru either: 129X1.129P2-Gabra1tm1.1Uru or B6.129P2-Gabra1tm1.1Uru	abnormal physiological response to xenobiotic	J:75895
	abnormal spatial reference memory	J:75895
	impaired behavioral response to xenobiotic	J:75895
	increased susceptibility to pharmacologically induced seizures	J:75895
Gabra1tm1Geh/Gabra1tm1Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	no abnormal phenotype detected	J:103381
Gabra1tm1Rmck/Gabra1tm1Rmck involves: 129S7/SvEvBrd * BALB/c * C57BL/6	abnormal behavioral response to xenobiotic	J:62214
Gabra1tm1Twr/Gabra1tm1Twr involves: 129S7/SvEvBrd * C57BL/6	abnormal GABA-mediated receptor currents	J:69290
	abnormal physiological response to xenobiotic	J:69290
	normal behavior/neurological phenotype	J:69290
	decreased body weight	J:69290
	decreased litter size	J:69290
	perinatal lethality, incomplete penetrance	J:69290
	poor grooming	J:69290
	tremors	J:69290
Gabra1tm2.1Geh/Gabra1+ involves: 129X1/SvJ * C57BL/6J	abnormal inhibitory postsynaptic currents	J:105293
	abnormal locomotor activation	J:105293
	abnormal locomotor behavior	J:105293
	abnormal maternal nurturing	J:105293
	decreased body weight	J:105293
	hunched posture	J:105293
	hyperresponsive	J:105293
	impaired coordination	J:105293
	postnatal lethality, incomplete penetrance	J:105293
	premature death	J:105293
	tremors	J:105293
Gabra1tm2Geh/Gabra1+ involves: 129X1/SvJ * C57BL/6J	impaired coordination	J:105293
Gabra1tm2Geh/Gabra1tm2Geh involves: 129X1/SvJ * C57BL/6J	abnormal locomotor activation	J:105293
	abnormal locomotor behavior	J:105293
	decreased body weight	J:105293
	hunched posture	J:105293
	hyperresponsive	J:105293
	impaired coordination	J:105293
	increased startle reflex	J:105293
	premature death	J:105293
	tremors	J:105293
Gabra1tm3Geh/Gabra1tm3Geh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	no abnormal phenotype detected	J:110982
Gabra1tm4Geh/Gabra1tm4Geh involves: 129X1/SvJ * C57BL/6 * SJL	normal behavior/neurological phenotype	J:144692
	increased exploration in new environment	J:144692