Fosb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fosb
FBJ osteosarcoma oncogene B
MGI:95575

25 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fosb^tm1.1Yun/Fosb⁺ B6.129S-Fosb^tm1.1Yun	abnormal locomotor activation	J:220448
	decreased anxiety-related response	J:220448
	increased exploration in new environment	J:220448
	increased locomotor activity	J:220448
Fosb^tm1.1Yun/Fosb^tm1.1Yun B6.129S-Fosb^tm1.1Yun	abnormal locomotor activation	J:220448
	decreased anxiety-related response	J:220448
	increased exploration in new environment	J:220448
	increased locomotor activity	J:220448
Fosb^{tm1b(KOMP)Wtsi}/Fosb^{tm1b(KOMP)Wtsi} C57BL/6N-Fosb^{tm1b(KOMP)Wtsi}/Ucd	abnormal heart morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal skin morphology	J:211773
	decreased bone mineral density	J:211773
	decreased mean corpuscular volume	J:211773
	enlarged heart	J:211773
	enlarged kidney	J:211773
Fosb^tm1Brv/Fosb^tm1Brv involves: 129S2/SvPas	tonic-clonic seizures	J:33415
Fosb^tm1Meg/Fosb⁺ involves: 129S4/SvJae * 129X1/SvJ * BALB/c	abnormal frequency of paradoxical sleep	J:64368
Fosb^tm1Meg/Fosb^tm1Meg either: (involves: 129S4/SvJae * 129X1/SvJ) or (involves: 129S4/SvJae * 129X1/SvJ * BALB/c)	abnormal maternal nurturing	J:34461
	abnormal nursing	J:34461
	abnormal parental behavior	J:34461
	abnormal pup retrieval	J:34461
	decreased body size	J:34461
Fosb^tm1Meg/Fosb^tm1Meg involves: 129S4/SvJae * 129X1/SvJ	abnormal seizure response to electrical stimulation	J:110995
Fosb^tm1Meg/Fosb^tm1Meg involves: 129S4/SvJae * 129X1/SvJ	reduced NMDA-mediated synaptic currents	J:110995
Fosb^tm1Meg/Fosb^tm1Meg involves: 129S4/SvJae * 129X1/SvJ * BALB/c	abnormal frequency of paradoxical sleep	J:64368
Fosb^tm2.1Yun/Fosb⁺ involves: 129S/SvEv * C57BL/6	abnormal locomotor activation	J:220448
Fosb^tm2.1Yun/Fosb^tm2.1Yun involves: 129S/SvEv * C57BL/6	abnormal depression-related behavior	J:220448
	abnormal emotion/affect behavior	J:220448
	abnormal learning/memory/conditioning	J:220448
	abnormal locomotor activation	J:220448
	impaired spatial learning	J:220448
	increased anxiety-related response	J:220448
	increased exploration in new environment	J:220448
	increased locomotor activity	J:220448

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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