Fcgr3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fcgr3
Fc receptor, IgG, low affinity III
MGI:95500

22 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fcgr3^{tm1b(EUCOMM)Hmgu}/Fcgr3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Fcgr3^{tm1b(EUCOMM)Hmgu}/H	abnormal gait	J:211773
	decreased circulating calcium level	J:211773
	decreased circulating creatine kinase level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	increased anxiety-related response	J:211773
	increased heart rate	J:211773
	tremors	J:211773
Fcgr3^tm1Jsv/Fcgr3^tm1Jsv B6.129P2-Fcgr3^tm1Jsv/J	abnormal leukocyte cell number	J:78297
	abnormal neutrophil physiology	J:78297
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:126520
	decreased susceptibility to induced arthritis	J:106191
	impaired neutrophil recruitment	J:78297
	increased neutrophil cell number	J:78297
Fcgr3^tm1Jsv/Fcgr3^tm1Jsv involves: 129P2/OlaHsd * C57BL/6	abnormal dendritic cell antigen presentation	J:83995
	abnormal type I hypersensitivity reaction	J:83995
	decreased mast cell degranulation	J:35057
	decreased susceptibility to autoimmune hemolytic anemia	J:83995
	decreased susceptibility to type II hypersensitivity reaction	J:35057
	impaired macrophage phagocytosis	J:35057
	impaired natural killer cell mediated cytotoxicity	J:35057
Fcgr3^tm1Ttk/Fcgr3^tm1Ttk involves: 129X1/SvJ	decreased susceptibility to type I hypersensitivity reaction	J:107371

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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