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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2
MGI:95413
75 phenotypes from 6 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ercc2Mhdarco15/Ercc2+
C3HeB/FeJ-Ercc2Mhdarco15
abnormal response to radiation J:223515
Ercc2Mhdarco15/Ercc2Mhdarco15
C3HeB/FeJ-Ercc2Mhdarco15
abnormal lens morphology J:223515
decreased body size J:223515
developmental cataract J:223515
female infertility J:223515
lens vacuoles J:223515
microphthalmia J:223515
nuclear cataract J:223515
normal reproductive system phenotype J:223515
rough coat J:223515
small lens J:223515
Ercc2tm1Jhjh/Ercc2tm1Jhjh
involves: 129P2/OlaHsd * C57BL/6
embryonic lethality before implantation, complete penetrance J:45017
Ercc2tm1Jhjh/Ercc2tm2(ERCC2)Jhjh
involves: 129P2/OlaHsd * C57BL/6
abnormal hair cuticle J:48256
abnormal hair follicle morphology J:48256
abnormal hemoglobin J:48256
acanthosis J:48256
alopecia J:48256
anemia J:48256
brittle hair J:48256
cachexia J:48256
decreased erythrocyte cell number J:48256
decreased hematocrit J:48256
decreased total body fat amount J:48256
greasy coat J:48256
hyperkeratosis J:48256
increased cellular sensitivity to ultraviolet irradiation J:116054
increased incidence of tumors by chemical induction J:48256
increased incidence of tumors by UV-induction J:48256
increased skin tumor incidence J:48256
postnatal growth retardation J:48256
premature death J:48256
scaly skin J:48256
thick skin J:48256
tremors J:48256
Ercc2tm1Jmch/Ercc2tm1Jmch
involves: 129P2/OlaHsd * C57BL/6
embryonic lethality before implantation, complete penetrance J:116054
Ercc2tm1Jmch/Ercc2tm2(ERCC2)Jhjh
involves: 129P2/OlaHsd * C57BL/6
decreased cellular sensitivity to ultraviolet irradiation J:116054
focal dorsal hair loss J:116054
normal growth/size/body region phenotype J:116054
normal mortality/aging J:116054
Ercc2tm2(ERCC2)Jhjh/Ercc2tm2(ERCC2)Jhjh
involves: 129P2/OlaHsd
normal immune system phenotype J:47993
increased cellular sensitivity to ultraviolet irradiation J:145759
Ercc2tm2(ERCC2)Jhjh/Ercc2tm2(ERCC2)Jhjh
involves: 129P2/OlaHsd * C57BL/6
abnormal cell physiology J:112689
abnormal circulating amino acid level J:76608
abnormal coat/ hair morphology J:48256
abnormal epidermis stratum granulosum morphology J:116054
abnormal fat cell morphology J:48256
abnormal hair follicle morphology J:48256
abnormal ovulation J:76608
abnormal sebaceous gland morphology J:116054
abnormal skeleton morphology J:48256
acanthosis J:48256, J:116054
alopecia J:48256
anemia J:76608, J:116054
brittle hair J:48256, J:116054
cachexia J:48256, J:76608, J:116054
decreased bone mineral density J:76608
decreased erythrocyte cell number J:76608
decreased hematocrit J:76608
decreased hemoglobin content J:76608
disproportionate dwarf J:48256
enlarged hair follicles J:48256
enlarged sebaceous gland J:76608
enlarged spleen J:76608
greasy coat J:48256, J:116054
hyperkeratosis J:48256, J:116054
increased incidence of induced tumors J:48256
kyphosis J:76608, J:116054
normal neoplasm J:112689
osteoporosis J:76608, J:116054
postnatal growth retardation J:48256, J:116054
premature aging J:76608
premature death J:48256, J:116054
reduced female fertility J:48256, J:76608
scaly skin J:48256
sparse hair J:116054
thick skin J:48256
tremors J:48256
white spotting J:76608
Ercc2tm2(ERCC2)Jhjh/Ercc2tm2Jmch
involves: 129P2/OlaHsd * C57BL/6
anemia J:116054
brittle hair J:116054
decreased cellular sensitivity to ultraviolet irradiation J:116054
focal dorsal hair loss J:116054
normal growth/size/body region phenotype J:116054
normal integument phenotype J:116054
normal mortality/aging J:116054
postnatal growth retardation J:116054
normal skeleton phenotype J:116054
Ercc2tm2(ERCC2)Jhjh/Ercc2tm3Jhjh
involves: 129P2/OlaHsd * C57BL/6
normal integument phenotype J:116054
Ercc2tm2Jmch/Ercc2tm2Jmch
involves: 129P2/OlaHsd * C57BL/6
embryonic lethality before implantation, complete penetrance J:116054
Ercc2tm3Jhjh/Ercc2tm3Jhjh
involves: 129 * C57BL/6J
astrocytosis J:179808
microgliosis J:179808
Ercc2tm3Jhjh/Ercc2tm3Jhjh
involves: 129P2/OlaHsd * C57BL/6
increased cellular sensitivity to ultraviolet irradiation J:116054
Ercc2tm3Jhjh/Ercc2tm3Jhjh
involves: 129P2/OlaHsd * C57BL/6 * FVB
abnormal DNA repair J:112689
abnormal testis morphology J:112689
acanthosis J:112689
cachexia J:112689
corneal opacity J:112689
decreased exploration in new environment J:112689
decreased tumor latency J:112689
normal hematopoietic system phenotype J:112689
increased cellular sensitivity to ultraviolet irradiation J:112689
increased incidence of tumors by UV-induction J:112689
normal integument phenotype J:112689
limb grasping J:112689
normal nervous system phenotype J:112689
postnatal growth retardation J:112689
premature death J:112689
reddish skin J:112689
normal reproductive system phenotype J:112689
skin photosensitivity J:112689

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory