Eif2s1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
MGI:95299

13 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Eif2s1^em1(IMPC)Mbp/Eif2s1⁺ C57BL/6N-Eif2s1^em1(IMPC)Mbp/MbpMmucd	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	enlarged spleen	J:211773
	increased bone mineral content	J:211773
Eif2s1^em1(IMPC)Mbp/Eif2s1^em1(IMPC)Mbp C57BL/6N-Eif2s1^em1(IMPC)Mbp/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Eif2s1^tm1Rjk/Eif2s1^tm1Rjk involves: 129S1/Sv * 129X1/SvJ	abnormal suckling behavior	J:70004
	decreased circulating insulin level	J:70004
	decreased insulin secretion	J:70004
	hypoglycemia	J:70004
	neonatal lethality, complete penetrance	J:70004

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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