Col5a2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Col5a2
collagen, type V, alpha 2
MGI:88458

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col5a2^tm1.1Dgr/Col5a2⁺ involves: 129S7/SvEvBrd * C57BL/6	no abnormal phenotype detected	J:223298
Col5a2^tm1.2Dgr/Col5a2⁺ involves: 129S7/SvEvBrd * C57BL/6 * DBA/2	abnormal cardiovascular system physiology	J:223298
	abnormal cutaneous collagen fibril morphology	J:223298
	abnormal skin physiology	J:223298
	decreased skin tensile strength	J:223298
Col5a2^tm1.2Dgr/Col5a2^tm1.2Dgr involves: 129S7/SvEvBrd * C57BL/6 * DBA/2	abnormal cutaneous collagen fibril morphology	J:223298
	blood vessel congestion	J:223298
	embryonic lethality during organogenesis, complete penetrance	J:223298
	pallor	J:223298
Col5a2^tm1Rmz/Col5a2^tm1Rmz either: (involves: 129S4/SvJae * 129T2/SvEms) or (involves: 129S4/SvJae * C57BL/6)	abnormal cornea morphology	J:22301
	abnormal cutaneous collagen fibril morphology	J:22301
	abnormal hypodermis morphology	J:22301
	abnormal skeleton development	J:22301
	decreased body size	J:22301
	decreased body weight	J:22301
	decreased corneal stroma thickness	J:22301
	decreased skin tensile strength	J:22301
	decreased survivor rate	J:22301
	hunched posture	J:22301
	lordokyphosis	J:22301
	neonatal lethality, incomplete penetrance	J:22301
	postnatal lethality, incomplete penetrance	J:22301
	pup cannibalization	J:22301
	respiratory distress	J:22301
	spontaneous skin ulceration	J:22301
	thick hypodermis	J:22301
	thin dermal layer	J:22301

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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