About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Chd1
chromodomain helicase DNA binding protein 1
MGI:88393
28 phenotypes from 4 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Chd1tm1.1Alsr/Chd1tm1.1Alsr
involves: BALB/cJ * C57BL/6 * C57BL/6NCrl
no abnormal phenotype detected J:231724
Chd1tm1b(KOMP)Rsan/Chd1tm1b(KOMP)Rsan
involves: 129P2/OlaHsd * C57BL/6J
abnormal cell cycle J:217689
abnormal developmental patterning J:217689
abnormal embryo development J:217689
abnormal mesoderm development J:217689
abnormal rostral-caudal axis patterning J:217689
absent anterior visceral endoderm J:217689
absent extraembryonic ectoderm J:217689
decreased embryo size J:217689
embryonic lethality, complete penetrance J:217689
failure to gastrulate J:217689
increased embryonic epiblast cell apoptosis J:217689
small embryonic epiblast J:217689
Chd1tm1b(KOMP)Wtsi/Chd1+
C57BL/6N-Chd1tm1b(KOMP)Wtsi/Tcp
abnormal embryo size J:211773
abnormal eye morphology J:211773
abnormal maxilla morphology J:211773
abnormal tooth morphology J:211773
anophthalmia J:211773
decreased bone mineral density J:211773
decreased hemoglobin content J:211773
decreased lean body mass J:211773
decreased mean corpuscular hemoglobin concentration J:211773
decreased red blood cell distribution width J:211773
embryonic growth retardation J:211773
increased hematocrit J:211773
Chd1tm1b(KOMP)Wtsi/Chd1tm1b(KOMP)Wtsi
C57BL/6N-Chd1tm1b(KOMP)Wtsi/Tcp
embryonic lethality prior to organogenesis J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Chd1tm1c(KOMP)Rsan/Chd1tm1c(KOMP)Rsan
Edil3Tg(Sox2-cre)1Amc/?
involves: 129P2/OlaHsd * C57BL/6J * CBA
embryonic lethality, complete penetrance J:217689

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory