Cdsn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdsn
corneodesmosin
MGI:3505689

35 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdsn^tm1.1Ics/Cdsn^tm1.1Ics Tg(KRT14-cre)1Ipc/0 involves: 129S2/SvPas * C57BL/6 * SJL	abnormal epidermal layer morphology	J:153292
	abnormal skin condition	J:153292
	absent epidermis stratum corneum	J:153292
	decreased skin tensile strength	J:153292
	dermal cyst	J:153292
	epidermal hyperplasia	J:153292
	hairless	J:153292
	hyperkeratosis	J:153292
	impaired skin barrier function	J:153292
	increased skin papilloma incidence	J:153292
	mixed cellular infiltration to dermis	J:153292
	neonatal lethality, complete penetrance	J:153292
	parakeratosis	J:153292
	spontaneous skin ulceration	J:153292
Cdsn^tm1.1Ics/Cdsn^tm1.1Ics Tg(KRT14-cre/ERT2)1Ipc/0 involves: 129S2/SvPas	acanthosis	J:153292
	distended hair follicles	J:153292
	hair follicle degeneration	J:153292
	hyperkeratosis	J:153292
	impaired skin barrier function	J:153292
	parakeratosis	J:153292
	premature death	J:153292
	scaly skin	J:153292
	sebaceous gland hypertrophy	J:153292
	skin inflammation	J:153292
	spontaneous skin ulceration	J:153292
	weight loss	J:153292
Cdsn^{tm1b(EUCOMM)Hmgu}/Cdsn⁺ C57BL/6N-Cdsn^{tm1b(EUCOMM)Hmgu}/Ieg	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	increased total retina thickness	J:211773
Cdsn^{tm1b(EUCOMM)Hmgu}/Cdsn^{tm1b(EUCOMM)Hmgu} C57BL/6N-Cdsn^{tm1b(EUCOMM)Hmgu}/Ieg	preweaning lethality, complete penetrance	J:211773
Cdsn^tm1Mmat/Cdsn⁺ involves: C57BL/6 * CBA	normal integument phenotype	J:134613
Cdsn^tm1Mmat/Cdsn^tm1Mmat involves: C57BL/6 * CBA	abnormal capillary morphology	J:134613
	abnormal epidermal layer morphology	J:134613
	abnormal epidermis stratum corneum morphology	J:134613
	abnormal epidermis stratum granulosum morphology	J:134613
	abnormal hair follicle morphology	J:134613
	abnormal hair shaft morphology	J:134613
	acanthosis	J:134613
	alopecia	J:134613
	dilated vasculature	J:134613
	hyperkeratosis	J:134613
	mixed cellular infiltration to dermis	J:134613
	neonatal lethality, complete penetrance	J:134613
	parakeratosis	J:134613
	psoriasis	J:134613

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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