Rasgrp3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rasgrp3
RAS, guanyl releasing protein 3
MGI:3028579

11 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rasgrp3^{em1(IMPC)Wtsi}/Rasgrp3^{em1(IMPC)Wtsi} C57BL/6N-Rasgrp3^{em1(IMPC)Wtsi}/Wtsi	abnormal eye morphology	J:211773
	abnormal uterus morphology	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean platelet volume	J:211773
	increased CD8-positive, naive alpha-beta T cell number	J:211773
Rasgrp3^{Gt(Pt1-ATG)1Vb}/Rasgrp3^{Gt(Pt1-ATG)1Vb} involves: CD-1	no abnormal phenotype detected	J:95118
Rasgrp3^tm1Jstn/Rasgrp3^tm1Jstn involves: 129P3/J * C57BL/6J	abnormal humoral immune response	J:108677
	decreased B cell number	J:108677
	decreased IgG1 level	J:108677
	decreased IgG2a level	J:108677
	decreased IgG level	J:108677

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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