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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mir146
microRNA 146
MGI:2676831
15 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Cd40tm1Kik/Cd40+
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Tg(Cr2-cre)3Cgn/0
involves: 129P2/OlaHsd * C57BL/6
normal immune system phenotype J:266124
increased T follicular helper cell number J:266124
Foxp3tm1.1Ayr/Foxp3tm1.1Ayr
Mir146tm1.1Bal/Mir146tm1.1Bal
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal lymphocyte physiology J:167922
blepharitis J:167922
conjunctivitis J:167922
decreased interferon-gamma secretion J:167922
dermatitis J:167922
increased regulatory T cell number J:167922
premature aging J:167922
Mir146tm1.1Bal/Mir146tm1.1Bal
Nfkb1tm1Bal/Nfkb1tm1Bal
involves: 129P2/OlaHsd * C57BL/6
normal hematopoietic system phenotype J:173230
Mir146tm1.1Bal/Mir146tm1.1Bal
Tifabtm1.1Dsta/Tifabtm1.1Dsta
involves: 129 * C57BL/6 * C57BL/6J
abnormal hematopoietic stem cell morphology J:229024
decreased lymphocyte cell number J:229024
decreased neutrophil cell number J:229024
Mir146tm1.1Lfl/Mir146tm1.1Lfl
Mir146btm1.1Lfl/Mir146btm1.1Lfl
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2
increased germinal center B cell number J:266124
increased IgG level J:266124
increased T follicular helper cell number J:266124

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory