Mir146 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mir146
microRNA 146
MGI:2676831

15 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd40^tm1Kik/Cd40⁺ Mir146^tm1.1Lfl/Mir146^tm1.1Lfl Tg(Cr2-cre)3Cgn/0 involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:266124
	increased T follicular helper cell number	J:266124
Foxp3^tm1.1Ayr/Foxp3^tm1.1Ayr Mir146^tm1.1Bal/Mir146^tm1.1Bal involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal lymphocyte physiology	J:167922
	blepharitis	J:167922
	conjunctivitis	J:167922
	decreased interferon-gamma secretion	J:167922
	dermatitis	J:167922
	increased regulatory T cell number	J:167922
	premature aging	J:167922
Mir146^tm1.1Bal/Mir146^tm1.1Bal Nfkb1^tm1Bal/Nfkb1^tm1Bal involves: 129P2/OlaHsd * C57BL/6	normal hematopoietic system phenotype	J:173230
Mir146^tm1.1Bal/Mir146^tm1.1Bal Tifab^tm1.1Dsta/Tifab^tm1.1Dsta involves: 129 * C57BL/6 * C57BL/6J	abnormal hematopoietic stem cell morphology	J:229024
	decreased lymphocyte cell number	J:229024
	decreased neutrophil cell number	J:229024
Mir146^tm1.1Lfl/Mir146^tm1.1Lfl Mir146b^tm1.1Lfl/Mir146b^tm1.1Lfl Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * DBA/2	increased germinal center B cell number	J:266124
	increased IgG level	J:266124
	increased T follicular helper cell number	J:266124

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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