Akap13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akap13
A kinase anchor protein 13
MGI:2676556

44 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akap13^em1(IMPC)Mbp/Akap13^em1(IMPC)Mbp C57BL/6N-Akap13^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal gallbladder morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged gallbladder	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
	improved glucose tolerance	J:211773
	microphthalmia	J:211773
	small liver	J:211773
Akap13^{Gt(AG0213)Wtsi}/Akap13^{Gt(AG0213)Wtsi} involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:231257
Akap13^{Gt(CSJ288)Byg}/Akap13^{Gt(CSJ288)Byg} involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:231257
Akap13^{Gt(CSJ306)Byg}/Akap13^{Gt(CSJ306)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal response of heart to induced stress	J:231257
	cardiac interstitial fibrosis	J:231257
	decreased ventricle muscle contractility	J:231257
	normal mortality/aging	J:231257
Akap13^tm1Segj/Akap13⁺ involves: 129	abnormal lymphocyte physiology	J:111574
	abnormal splenocyte physiology	J:181088
	decreased B cell number	J:181088
	decreased IgG1 level	J:181088
	decreased spleen B cell follicle size	J:181088
	decreased spleen weight	J:181088
	decreased splenocyte number	J:181088
	decreased transitional stage T2 B cell number	J:181088
	increased transitional stage T1 B cell number	J:181088
	reduced fertility	J:181087
	small spleen	J:181088
	spleen hypoplasia	J:181088
Akap13^tm1Segj/Akap13^tm1Segj involves: 129	prenatal lethality, complete penetrance	J:111574
Akap13^tm1Segj/Akap13^tm1Segj involves: 129 * C57BL/6	abnormal heart development	J:181087
	abnormal nuchal region morphology	J:181087
	abnormal sarcomere morphology	J:181087
	decreased forebrain size	J:181087
	embryonic growth retardation	J:181087
	embryonic lethality during organogenesis, complete penetrance	J:181087
	enlarged heart	J:181087
	myocardial trabeculae hypoplasia	J:181087
	pericardial effusion	J:181087
	small first pharyngeal arch	J:181087
	thin myocardium	J:181087

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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