Ccar2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccar2
cell cycle activator and apoptosis regulator 2
MGI:2444228

15 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccar2^Gt(XN876)Byg/Ccar2^Gt(XN876)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal liver physiology	J:156677
	decreased susceptibility to diet-induced hepatic steatosis	J:156677
	decreased tumor necrosis factor secretion	J:156677
Ccar2^tm1Dac/Ccar2^tm1Dac involves: 129 * C57BL/6J	decreased energy expenditure	J:228688
	decreased locomotor activity	J:228688
	decreased oxygen consumption	J:228688
	impaired glucose tolerance	J:228688
	increased circulating insulin level	J:228688
	increased hepatic glucose production	J:228688
	increased susceptibility to diet-induced obesity	J:228688
	increased susceptibility to weight gain	J:228688
	increased total body fat amount	J:228688
	increased unsaturated fatty acids level	J:228688
	insulin resistance	J:228688
	normal neoplasm	J:228688

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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