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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Fscn2
fascin actin-bundling protein 2
MGI:2443337
14 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Fscn2ahl8/Fscn2ahl8
DBA/2J
abnormal auditory brainstem response J:139223
decreased inner hair cell stereocilia number J:162868
decreased outer hair cell stereocilia number J:162868
increased or absent threshold for auditory brainstem response J:162868
increased susceptibility to age-related hearing loss J:139223, J:162868
Fscn2tm1Sykk/Fscn2+
involves: 129S4/SvJae * C57BL/6
abnormal cone electrophysiology J:103713
abnormal eye electrophysiology J:103713
abnormal retina morphology J:103713
abnormal rod electrophysiology J:103713
retinal degeneration J:103713
short photoreceptor outer segment J:103713
thin retinal inner nuclear layer J:103713
thin retinal outer nuclear layer J:103713
Fscn2tm1Sykk/Fscn2tm1Sykk
involves: 129S4/SvJae * C57BL/6
abnormal cone electrophysiology J:103713
abnormal eye electrophysiology J:103713
abnormal retina morphology J:103713
abnormal rod electrophysiology J:103713
retinal degeneration J:103713
short photoreceptor outer segment J:103713
thin retinal inner nuclear layer J:103713
thin retinal outer nuclear layer J:103713
Fscn2tm2Sykk/Fscn2+
involves: 129S4/SvJae * C57BL/6
abnormal cone electrophysiology J:103713
abnormal eye electrophysiology J:103713
abnormal retina morphology J:103713
abnormal rod electrophysiology J:103713
retinal degeneration J:103713
short photoreceptor outer segment J:103713
thin retinal inner nuclear layer J:103713
thin retinal outer nuclear layer J:103713
Fscn2tm2Sykk/Fscn2tm2Sykk
involves: 129S4/SvJae * C57BL/6
abnormal cone electrophysiology J:103713
abnormal eye electrophysiology J:103713
abnormal photoreceptor outer segment morphology J:103713
abnormal retina morphology J:103713
abnormal rod electrophysiology J:103713
retinal degeneration J:103713
short photoreceptor outer segment J:103713
thin retinal inner nuclear layer J:103713
thin retinal outer nuclear layer J:103713
Tg(RP24-180N9)2Kjn/0
DBA/2J-Tg(RP24-180N9)2Kjn/Kjn
abnormal auditory brainstem response J:162868

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory