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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Cgas
cyclic GMP-AMP synthase
MGI:2442261
19 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
C57BL/6N-Cgastm1a(EUCOMM)Hmgu
abnormal dendritic cell physiology J:201167
abnormal immune cell physiology J:201167
abnormal macrophage physiology J:201167
abnormal plasmacytoid dendritic cell physiology J:201167
decreased circulating interferon-alpha level J:201167
decreased circulating interferon-beta level J:201167
increased susceptibility to Herpesvirales infection J:201167
increased susceptibility to Herpesvirales infection induced morbidity/mortality J:201167
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
C57BL/6N-Cgastm1a(EUCOMM)Hmgu/Ics
abnormal behavior J:165965
abnormal tail movements J:165965
decreased grip strength J:165965
Cgastm1a(EUCOMM)Hmgu/Cgastm1a(EUCOMM)Hmgu
involves: C57BL/6N
abnormal interferon secretion J:234263
Cgastm1d(EUCOMM)Hmgu/Cgastm1d(EUCOMM)Hmgu
involves: BALB/c * C57BL/6JJcl * C57BL/6N
increased susceptibility to Flaviviridae infection J:207826
increased susceptibility to Flaviviridae infection induced morbidity/mortality J:207826
increased susceptibility to Herpesvirales infection J:207826
increased susceptibility to Poxviridae infection J:207826
increased susceptibility to Poxviridae infection induced morbidity/mortality J:207826
Cgastm1d(EUCOMM)Hmgu/Cgastm1d(EUCOMM)Hmgu
involves: C57BL/6N
normal hematopoietic system phenotype J:265023
normal immune system phenotype J:265023
increased susceptibility to Retroviridae infection J:265023

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory