Ggnbp2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ggnbp2
gametogenetin binding protein 2
MGI:2387356

39 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ggnbp2^{Gt(IST12476F10)Tigm}/Ggnbp2^{Gt(IST12476F10)Tigm} C57BL/6-Ggnbp2^{Gt(IST12476F10)Tigm}	abnormal placenta junctional zone morphology	J:232444
	abnormal placenta labyrinth morphology	J:232444
	abnormal placental labyrinth vasculature morphology	J:232444
	normal embryo phenotype	J:232444
	lethality throughout fetal growth and development, complete penetrance	J:232444
	pale placenta	J:232444
	pallor	J:232444
Ggnbp2^{Gt(IST12476F10)Tigm}/Ggnbp2^{Gt(IST12476F10)Tigm} involves: 129 * C57BL/6N	abnormal acrosome assembly	J:249037
	abnormal acrosome morphology	J:249037
	abnormal epididymis morphology	J:249037
	abnormal manchette assembly	J:249037
	abnormal seminiferous tubule epithelium morphology	J:249037
	abnormal seminiferous tubule morphology	J:249037
	abnormal spermatid morphology	J:249037
	abnormal testis physiology	J:249037
	arrest of spermiogenesis	J:249037
	azoospermia	J:249037
	decreased male germ cell number	J:249037
	decreased survivor rate	J:249037
	decreased testis weight	J:249037
	detached acrosome	J:249037
	ectopic manchette	J:249037
	normal homeostasis/metabolism phenotype	J:249037
	male infertility	J:249037
	prenatal lethality, incomplete penetrance	J:249037
	normal reproductive system phenotype	J:249037
	small epididymis	J:249037
	small seminiferous tubules	J:249037
	small testis	J:249037
Ggnbp2^{tm1b(KOMP)Wtsi}/Ggnbp2⁺ C57BL/6N-Ggnbp2^{tm1b(KOMP)Wtsi}/Tcp	decreased circulating total protein level	J:211773
	edema	J:211773
	increased circulating alanine transaminase level	J:211773
	shortened QRS complex duration	J:211773
Ggnbp2^{tm1b(KOMP)Wtsi}/Ggnbp2^{tm1b(KOMP)Wtsi} C57BL/6N-Ggnbp2^{tm1b(KOMP)Wtsi}/Tcp	abnormal embryo size	J:211773
	anophthalmia	J:211773
	edema	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Ggnbp2^tm1Bbs/Ggnbp2^tm1Bbs involves: 129S6/SvEvTac * C57BL/6	abnormal seminiferous tubule epithelium morphology	J:270533
	abnormal seminiferous tubule morphology	J:270533
	abnormal spermatogenesis	J:270533
	azoospermia	J:270533
	decreased Sertoli cell number	J:270533
	decreased survivor rate	J:270533
	increased testis apoptosis	J:270533
	male infertility	J:270533
	prenatal lethality, incomplete penetrance	J:270533

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