Usp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Usp1
ubiquitin specific peptidase 1
MGI:2385198

33 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Usp1^tm1.1Ada/Usp1^tm1.1Ada C57BL/6-Usp1^tm1.1Ada	abnormal male germ cell morphology	J:146616
	abnormal spermatid morphology	J:146616
	abnormal spermatocyte morphology	J:146616
	abnormal spermatogonia morphology	J:146616
	cyanosis	J:146616
	decreased body weight	J:146616
	decreased bone marrow cell number	J:146616
	decreased oocyte number	J:146616
	edema	J:146616
	increased mortality induced by gamma-irradiation	J:146616
	induced chromosome breakage	J:146616
	male infertility	J:146616
	oligozoospermia	J:146616
	postnatal lethality, incomplete penetrance	J:146616
	reduced female fertility	J:146616
	seminiferous tubule degeneration	J:146616
	small testis	J:146616
Usp1^{tm1b(KOMP)Wtsi}/Usp1^{tm1b(KOMP)Wtsi} C57BL/6N-Usp1^{tm1b(KOMP)Wtsi}/Wtsi	abnormal eyelid aperture	J:211773
	abnormal snout morphology	J:211773
	decreased body length	J:211773
	decreased erythrocyte cell number	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating creatinine level	J:211773
	increased circulating insulin level	J:211773
	increased circulating potassium level	J:211773
	increased mean corpuscular hemoglobin	J:211773
Usp1^{tm1d(KOMP)Wtsi}/Usp1^{tm1d(KOMP)Wtsi} involves: C57BL/6N	abnormal osteoid morphology	J:207363
	decreased bone mineral density	J:207363
	decreased bone volume	J:207363
	decreased circulating alkaline phosphatase level	J:207363
	delayed bone ossification	J:207363
	increased bone resorption	J:207363
	normal skeleton phenotype	J:207363

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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