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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Adgrf5
adhesion G protein-coupled receptor F5
MGI:2182928
44 phenotypes from 6 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Adgrf5m1Btlr/Adgrf5m1Btlr
C57BL/6J-Adgrf5m1Btlr
increased circulating glucose level J:225045
Adgrf5tm1.1Bstc/Adgrf5tm1.2Bstc
Tg(Sftpc-cre)1Blh/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2
pulmonary alveolar proteinosis J:196943
Adgrf5tm1.1Bstc/Adgrf5tm1.2Bstc
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J
abnormal lipid level J:196943
increased cholesterol level J:196943
increased surfactant secretion J:196943
Adgrf5tm1.1Bstc/Adgrf5tm1.2Bstc
Tg(Tek-cre)12Flv/0
involves: 129S4/SvJae * C3H * C57BL/6 * C57BL/6J
normal respiratory system phenotype J:196943
Adgrf5tm1.1Bstc/Adgrf5tm1.2Bstc
Tg(Vav1-icre)A2Kio/0
involves: 129S4/SvJae * C57BL/6J * C57BL/10 * CBA/Ca
normal respiratory system phenotype J:196943
Adgrf5tm1.2Bstc/Adgrf5tm1.2Bstc
involves: 129S4/SvJae * C57BL/6J
abnormal lipid level J:196943
abnormal surfactant physiology J:196943
abnormal type II pneumocyte morphology J:196943
decreased body weight J:196943
increased alveolar lamellar body number J:196943
increased cholesterol level J:196943
increased macrophage derived foam cell number J:196943
increased surfactant secretion J:196943
premature death J:196943
pulmonary alveolar proteinosis J:196943
respiratory distress J:196943
Adgrf5tm1.2Jpbs/Adgrf5tm1.2Jpbs
BALB/c-Adgrf5tm1.2Jpbs
abnormal alveolar macrophage morphology J:221769
abnormal lung morphology J:221769
abnormal pulmonary alveolus morphology J:221769
abnormal respiration J:221769
abnormal respiratory system physiology J:221769
abnormal surfactant composition J:221769
abnormal surfactant physiology J:221769
normal growth/size/body region phenotype J:221769
increased surfactant secretion J:221769
respiratory distress J:221769
tachypnea J:221769
Adgrf5tm1b(KOMP)Wtsi/Adgrf5tm1b(KOMP)Wtsi
C57BL/6N-Adgrf5tm1b(KOMP)Wtsi/Tcp
abnormal retina morphology J:211773
decreased body length J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating cholesterol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
decreased leukocyte cell number J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
decreased total body fat amount J:211773
impaired glucose tolerance J:211773
increased blood urea nitrogen level J:211773
increased circulating bilirubin level J:211773
increased circulating calcium level J:211773
increased grip strength J:211773
increased red blood cell distribution width J:211773
short tibia J:211773
Adgrf5tm1Shiro/Adgrf5tm1Shiro
B6.Cg-Adgrf5tm1Shiro
abnormal alveolar macrophage morphology J:204701
abnormal pulmonary alveolus morphology J:204701
emphysema J:204701
increased lung weight J:204701
increased macrophage cell number J:204701
increased surfactant secretion J:204701
increased type II pneumocyte number J:204701

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory