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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Taf4
TATA-box binding protein associated factor 4
MGI:2152346
25 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Taf4tm1.1Idvd/Taf4tm1.1Idvd
Not Specified
decreased fibroblast apoptosis J:125257
embryonic lethality during organogenesis, complete penetrance J:125257
increased fibroblast proliferation J:125257
Taf4tm1Idvd/Taf4tm1Idvd
Tg(KRT14-cre)1Ipc/0
Not Specified
impaired skin barrier function J:124111
neonatal lethality, complete penetrance J:124111
thin skin J:124111
translucent skin J:124111
weight loss J:124111
Taf4tm1Idvd/Taf4tm1Idvd
Tg(KRT14-cre/ERT2)1Ipc/0
involves: C57BL/6 * SJL
abnormal coat/ hair morphology J:124111
abnormal hair cycle J:124111
abnormal hair shaft morphology J:124111
abnormal skin condition J:124111
abnormal skin morphology J:124111
abnormal tail morphology J:124111
chronic inflammation J:124111
dermal cysts J:124111
dry skin J:124111
epidermal hyperplasia J:124111
impaired skin barrier function J:124111
increased incidence of tumors by chemical induction J:124111
increased keratinocyte proliferation J:124111
increased malignant tumor incidence J:124111
increased squamous cell carcinoma incidence J:124111
kinked tail J:124111
scaly skin J:124111
sparse hair J:124111

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory