Cnnm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cnnm2
cyclin M2
MGI:2151054

23 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cnnm2^{tm1.1(KOMP)Vlcg}/Cnnm2⁺ C57BL/6N-Cnnm2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal heart morphology	J:211773
	anophthalmia	J:211773
	enlarged heart	J:211773
	hemorrhage	J:211773
	hyperactivity	J:211773
	increased bone mineral density	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Cnnm2^{tm1.1(KOMP)Vlcg}/Cnnm2^{tm1.1(KOMP)Vlcg} C57BL/6N-Cnnm2^{tm1.1(KOMP)Vlcg}/Ucd	abnormal craniofacial morphology	J:211773
	abnormal head shape	J:211773
	abnormal head size	J:211773
	anophthalmia	J:211773
	embryonic growth retardation	J:211773
	hemorrhage	J:211773
	microcephaly	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	preweaning lethality, complete penetrance	J:211773
	spina bifida	J:211773
	syndactyly	J:211773
Cnnm2^tm1.1Hmik/Cnnm2⁺ involves: C57BL * C57BL/6J * DBA	abnormal homeostasis	J:303151
	decreased circulating magnesium level	J:303151
	decreased systemic arterial diastolic blood pressure	J:303151
	decreased systemic arterial systolic blood pressure	J:303151
	normal mortality/aging	J:303151
Cnnm2^tm1.1Hmik/Cnnm2^tm1.1Hmik involves: C57BL * C57BL/6J * DBA	lethality throughout fetal growth and development, complete penetrance	J:303151
Cnnm2^tm1Hmik/Cnnm2^tm1Hmik Tg(Six2-EGFP/cre)1Amc/0 involves: C57BL/6J * CD-1	decreased circulating magnesium level	J:303151
	decreased systemic arterial diastolic blood pressure	J:303151
	decreased systemic arterial systolic blood pressure	J:303151
	normal growth/size/body region phenotype	J:303151
	normal mortality/aging	J:303151

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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