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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Csnk1a1
casein kinase 1, alpha 1
MGI:1934950
23 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Csnk1a1tm1.1Ybn/Csnk1a1tm1.1Ybn
Tg(Vil-cre/ERT2)23Syr/0
involves: 129 * C57BL/6 * CD-1 * DBA/2
increased apoptosis J:204886
increased fibroblast apoptosis J:204886
Csnk1a1tm1.1Ybn/Csnk1a1tm1.2Ybn
involves: 129 * BALB/c * C57BL/6 * CD-1
normal mortality/aging J:204886
normal neoplasm J:204886
Csnk1a1tm1.2Ybn/Csnk1a1tm1.2Ybn
involves: 129 * BALB/c * C57BL/6 * CD-1
embryonic lethality, complete penetrance J:204886
Csnk1a1tm1c(KOMP)Wtsi/Csnk1a1+
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * C57BL/6N * CBA
abnormal erythroid lineage cell morphology J:216977
abnormal hematopoietic system morphology/development J:216977
abnormal megakaryocyte morphology J:216977
decreased bone marrow cell number J:216977
decreased common myeloid progenitor cell number J:216977
decreased hematopoietic stem cell number J:216977
decreased myeloid cell number J:216977
pancytopenia J:216977
premature death J:216977
Csnk1a1tm1c(KOMP)Wtsi/Csnk1a1tm1c(KOMP)Wtsi
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * C57BL/6N * CBA
abnormal blood cell morphology J:216977
abnormal hematopoietic stem cell physiology J:216977
abnormal liver morphology J:216977
abnormal liver physiology J:216977
abnormal myocardium layer morphology J:216977
abnormal spleen red pulp morphology J:216977
bone marrow failure J:216977
cardiac ischemia J:216977
decreased hematopoietic stem cell number J:216977
extramedullary hematopoiesis J:216977
premature death J:216977

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory