Dnaja3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnaja3
DnaJ heat shock protein family (Hsp40) member A3
MGI:1933786

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnaja3^tm1.1Jdl/Dnaja3^tm1.1Jdl Tg(Myhca-cre)1Abel/0 involves: 129X1/SvJ * C57BL/6J * FVB	abnormal myocardial fiber morphology	J:104462
	abnormal respiratory electron transport chain	J:104462
	abnormal sarcomere morphology	J:104462
	cardiac interstitial fibrosis	J:104462
	congestive heart failure	J:104462
	decreased locomotor activity	J:104462
	decreased myocardial fiber mitochondrial DNA content	J:104462
	decreased ventricle muscle contractility	J:104462
	dilated cardiomyopathy	J:104462
	dilated heart left ventricle	J:104462
	dilated heart right ventricle	J:104462
	dilated mitochondrion	J:104462
	embryonic growth retardation	J:104462
	embryonic lethality during organogenesis, incomplete penetrance	J:104462
	enlarged heart	J:104462
	increased cardiomyocyte apoptosis	J:104462
	pericardial effusion	J:104462
	premature death	J:104462
	trabecula carnea hypoplasia	J:104462
Dnaja3^tm1.2Jdl/Dnaja3^tm1.2Jdl involves: 129X1/SvJ * C57BL/6 * FVB/N	embryonic lethality between implantation and somite formation, complete penetrance	J:89091
Dnaja3^tm1Jdl/Dnaja3^tm1Jdl involves: 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:89091

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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