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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Slc26a5
solute carrier family 26, member 5
MGI:1933154
26 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Slc26a5mpc234H/Slc26a5mpc234H
involves: BALB/c * C3H/HeH * C57BL/6J
deafness J:234901
Slc26a5tm1Jnz/Slc26a5+
involves: 129S7/SvEvBrd * C57BL/6J
abnormal cochlear outer hair cell morphology J:79029
abnormal distortion product otoacoustic emission J:79029, J:118929
cochlear inner hair cell degeneration J:79029
cochlear outer hair cell degeneration J:79029
decreased body weight J:79029
decreased cochlear outer hair cell electromotility J:79029
impaired hearing J:79029, J:118929
increased or absent threshold for auditory brainstem response J:79029, J:91680
Slc26a5tm1Jnz/Slc26a5tm1Jnz
involves: 129S7/SvEvBrd
abnormal cochlear outer hair cell morphology J:145297
abnormal otoacoustic response J:160851
increased cochlear nerve compound action potential J:145297
Slc26a5tm1Jnz/Slc26a5tm1Jnz
involves: 129S7/SvEvBrd * C57BL/6J
abnormal Claudius cell morphology J:91680
abnormal distortion product otoacoustic emission J:79029, J:124148
absent cochlear microphonics J:79029
absent cochlear outer hair cell electromotility J:79029
absent distortion product otoacoustic emissions J:124148
cochlear ganglion degeneration J:91680
cochlear hair cell degeneration J:91680
cochlear inner hair cell degeneration J:79029, J:91680
cochlear outer hair cell degeneration J:79029, J:91680
deafness J:91680
decreased body weight J:79029
decreased cochlear microphonics J:105502, J:124148
decreased cochlear nerve compound action potential J:105502, J:124148
degeneration of organ of Corti supporting cells J:91680
impaired hearing J:79029
increased or absent threshold for auditory brainstem response J:79029, J:91680
organ of Corti degeneration J:91680
short cochlear outer hair cells J:79029, J:91680
Slc26a5tm2Jnz/Slc26a5tm2Jnz
involves: 129S6/SvEvTac * FVB/N
abnormal cochlear outer hair cell electromotility J:123299
Slc26a5tm3Jnz/Slc26a5tm3Jnz
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
abnormal cochlear outer hair cell physiology J:145297
decreased cochlear outer hair cell electromotility J:145297
decreased cochlear outer hair cell number J:145297
increased cochlear nerve compound action potential J:145297
Slc26a5tm4(cre/ERT2)Jnz/Slc26a5+
involves: 129S6/SvEvTac
normal hearing/vestibular/ear phenotype J:182720
Slc26a5tm4.1(cre/ERT2)Jnz/Slc26a5+
involves: 129S6/SvEvTac * C57BL/6
normal hearing/vestibular/ear phenotype J:182720
Slc26a5tm4.1(cre/ERT2)Jnz/Slc26a5tm4.1(cre/ERT2)Jnz
involves: 129S6/SvEvTac * C57BL/6
increased or absent threshold for auditory brainstem response J:182720

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory