Selenok Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Selenok
selenoprotein K
MGI:1931466

17 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Selenok^tm1.2Itl/Selenok^tm1.2Itl involves: BALB/cJ * C57BL/6	abnormal circulating chemokine level	J:169169
	abnormal macrophage physiology	J:169169
	abnormal neutrophil physiology	J:169169
	abnormal T cell physiology	J:169169
	decreased interleukin-6 secretion	J:169169
	decreased T cell proliferation	J:169169
	decreased tumor necrosis factor secretion	J:169169
	impaired neutrophil chemotaxis	J:169169
	increased susceptibility to Flaviviridae infection	J:169169
	increased susceptibility to Flaviviridae infection induced morbidity/mortality	J:169169
Selenok^{tm1a(EUCOMM)Wtsi}/Selenok^{tm1a(EUCOMM)Wtsi} C57BL/6N-Selenok^{tm1a(EUCOMM)Wtsi}/Wtsi	decreased circulating magnesium level	J:211773
	decreased lean body mass	J:211773
	decreased mean platelet volume	J:211773
	increased total body fat amount	J:211773
Selenok^{tm1b(EUCOMM)Wtsi}/Selenok^{tm1b(EUCOMM)Wtsi} C57BL/6N-Selenok^{tm1b(EUCOMM)Wtsi}/Wtsi	abnormal auditory brainstem response	J:211773
	abnormal spine curvature	J:211773
	abnormal vertebral arch morphology	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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