Piwil2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Piwil2
piwi-like RNA-mediated gene silencing 2
MGI:1930036

12 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Piwil2^tm1.1Doca/Piwil2^tm1.1Doca involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J	abnormal cell physiology	J:184034
	abnormal DNA methylation	J:184034
	abnormal male germ cell apoptosis	J:184034
	arrest of male meiosis	J:184034
	male infertility	J:184034
	testicular atrophy	J:184034
Piwil2^tm1.1Doca/Piwil2^tm2.1Doca Tg(Stra8-icre)1Reb/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/NJ	abnormal cell physiology	J:199259
	abnormal male germ cell apoptosis	J:199259
	decreased testis weight	J:199259
	male infertility	J:199259
Piwil2^tm1Nkn/Piwil2^tm1Nkn involves: 129S2/SvPas * C57BL/6	arrest of male meiosis	J:87735
	azoospermia	J:87735
	decreased testis weight	J:87735
	increased male germ cell apoptosis	J:87735
	male infertility	J:87735
	normal reproductive system phenotype	J:87735
Piwil2^tm1Nkn/Piwil2^tm1Nkn Tg(Piwil2)#Hsas/0 involves: 129S2/SvPas	normal reproductive system phenotype	J:192826
Piwil2^tm2.1Doca/Piwil2^tm2.1Doca Tg(Stra8-icre)1Reb/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/NJ	abnormal cell physiology	J:199259
	abnormal male germ cell apoptosis	J:199259
	decreased testis weight	J:199259
	male infertility	J:199259
Piwil2^tm2.2Doca/Piwil2^tm2.2Doca involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ * C57BL/6J	abnormal cell physiology	J:199259
	abnormal spermatocyte morphology	J:199259
	abnormal spermatogonia morphology	J:199259

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23