55 phenotypes from 12 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi B6.129P2-Stk4Gt(AJ0315)Wtsi	abnormal memory T cell number	J:142674
	abnormal T cell differentiation	J:142674
	decreased CD4-positive, alpha-beta T cell number	J:142674
	decreased CD8-positive, alpha-beta T cell number	J:142674
	decreased spleen white pulp amount	J:142674
	increased interferon-gamma secretion	J:142674
	increased interleukin-2 secretion	J:142674
	increased interleukin-4 secretion	J:142674
	increased T cell apoptosis	J:142674
	increased T cell proliferation	J:142674
Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi involves: 129 * C57BL/6	increased histiocytic sarcoma incidence	J:153945
Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi involves: 129P2/OlaHsd * C57BL/6J	normal mortality/aging	J:140710
Stk4m1Btlr/Stk4m1Btlr C57BL/6J-Stk4m1Btlr	abnormal humoral immune response	J:265233
	decreased B cell number	J:265233
	decreased CD4-positive, alpha-beta T cell number	J:265233
	decreased CD8-positive, alpha-beta T cell number	J:265233
	decreased IgD level	J:265233
	decreased single-positive T cell number	J:265233
	decreased T cell number	J:265233
	increased IgE level	J:265233
	increased IgM level	J:265233
	increased macrophage cell number	J:265233
	increased neutrophil cell number	J:265233
	increased NK cell number	J:265233
Stk4m1Mhda/Stk4+ C3HeB/FeJ-Stk4m1Mhda	no abnormal phenotype detected	J:82809
Stk4m2Btlr/Stk4m2Btlr C57BL/6J-Stk4m2Btlr	decreased B-1 B cell number	J:265237
	decreased B-2 B cell number	J:265237
	decreased CD4-positive, alpha-beta T cell number	J:265237
	decreased CD8-positive, alpha-beta T cell number	J:265237
	decreased CD8-positive, naive alpha-beta T cell number	J:265237
	decreased IgD level	J:265237
	decreased single-positive T cell number	J:265237
	decreased T cell number	J:265237
	increased B-1b cell number	J:265237
	increased central memory CD4-positive, alpha-beta T cell number	J:265237
	increased central memory CD8 positive, alpha-beta T cell number	J:265237
	increased dendritic cell number	J:265237
	increased effector memory CD4-positive, alpha-beta T cell number	J:265237
	increased effector memory CD8-positive, alpha-beta T cell number	J:265237
	increased IgE level	J:265237
	increased macrophage cell number	J:265237
	increased neutrophil cell number	J:265237
	increased NK cell number	J:265237
Stk4m3Btlr/Stk4m3Btlr C57BL/6J-Stk4m3Btlr	decreased CD4-positive, alpha-beta T cell number	J:265245
	decreased CD8-positive, alpha-beta T cell number	J:265245
	decreased single-positive T cell number	J:265245
	decreased T cell number	J:265245
Stk4m4Btlr/Stk4m4Btlr C57BL/6J-Stk4m4Btlr	decreased CD11b-high dendritic cell number	J:272536
	decreased IgD level	J:272536
	decreased IgG level	J:272536
	impaired humoral immune response	J:272536
	increased B-1b cell number	J:272536
	increased dendritic cell number	J:272536
Stk4m5Btlr/Stk4m5Btlr C57BL/6J-Stk4m5Btlr	abnormal CD4-positive T cell differentiation	J:272743
	abnormal T cell differentiation	J:272743
	decreased CD4-positive, alpha-beta T cell number	J:272743
	increased central memory CD4-positive, alpha-beta T cell number	J:272743
Stk4tm1.1Kina/Stk4tm1.1Kina involves: C57BL/6	abnormal B cell physiology	J:148791
	abnormal dendritic cell physiology	J:148791
	abnormal immune system organ morphology	J:148791
	abnormal leukocyte adhesion	J:148791
	abnormal leukocyte migration	J:148791
	abnormal marginal zone B cell morphology	J:148791
	abnormal Peyer's patch germinal center morphology	J:148791
	abnormal Peyer's patch T cell area morphology	J:148791
	abnormal spleen B cell follicle morphology	J:148791
	abnormal T cell physiology	J:148791
	decreased B cell number	J:148791
	decreased lymphocyte cell number	J:148791
	decreased marginal zone B cell number	J:148791
	decreased myeloid dendritic cell number	J:148791
	decreased spleen B cell follicle size	J:148791
	decreased T cell number	J:148791
	increased single-positive T cell number	J:148791
	increased T cell proliferation	J:148791
	thymus hyperplasia	J:148791
Stk4tm1.1Wtao/Stk4tm1.2Wtao Tg(Lck-cre)#Zhu/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL/J	decreased CD4-positive, alpha-beta T cell number	J:152323
	decreased CD8-positive, alpha-beta T cell number	J:152323
	decreased T cell number	J:152323
	increased single-positive T cell number	J:152323
	increased thymocyte number	J:152323
Stk4tm1.1Yy/Stk4tm1.1Yy involves: C57BL/6 * CBA	no abnormal phenotype detected	J:156541
Stk4tm1.2Wtao/Stk4tm1.2Wtao involves: 129S4/SvJaeSor * 129S6/SvEvTac	abnormal CD4-positive, alpha-beta T cell physiology	J:152323
	abnormal CD8-positive, alpha-beta T cell physiology	J:152323
	abnormal T cell physiology	J:152323
	decreased B cell number	J:152323
	decreased CD4-positive, alpha-beta T cell number	J:152323
	decreased CD8-positive, alpha-beta T cell number	J:152323
	decreased lymphocyte cell number	J:152323
	increased single-positive T cell number	J:152323
	increased thymocyte number	J:152323
Stk4tm1Dlim/Stk4tm1Dlim Not Specified	abnormal T cell physiology	J:155001
	decreased T cell number	J:155001