About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ireb2
iron responsive element binding protein 2
MGI:1928268
59 phenotypes from 5 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Ireb2tm1.1Eal/Ireb2tm1.1Eal
B6J.129-Ireb2tm1.1Eal
abnormal axon morphology J:217335
abnormal cerebellum white matter morphology J:217335
abnormal cerebral cortex morphology J:217335
abnormal corpus callosum morphology J:217335
abnormal dorsal striatum morphology J:217335
abnormal hippocampal pyramidal neuron dendrite morphology J:217335
abnormal hippocampus pyramidal cell morphology J:217335
abnormal iron homeostasis J:217335
abnormal iron level J:217335
abnormal oligodendrocyte morphology J:217335
abnormal Purkinje cell morphology J:217335
abnormal superior colliculus morphology J:217335
abnormal thalamus morphology J:217335
normal behavior/neurological phenotype J:217335
decreased brain iron level J:217335
decreased heart iron level J:217335
decreased hematocrit J:217335
decreased hemoglobin content J:217335
decreased locomotor activity J:217335
decreased mean corpuscular hemoglobin J:217335
decreased mean corpuscular hemoglobin concentration J:217335
decreased mean corpuscular volume J:217335
decreased mean platelet volume J:217335
decreased vertical activity J:217335
impaired coordination J:217335
increased brain iron level J:217335
increased circulating ferritin level J:217335
increased intestinal iron level J:217335
increased kidney iron level J:217335
increased liver iron level J:217335
increased porphyrin level J:217335
increased red blood cell distribution width J:217335
increased thermal nociceptive threshold J:217335
microcytic anemia J:217335
normal nervous system phenotype J:217335
porphyria J:217335
normal skeleton phenotype J:217335
thrombocytopenia J:217335
Ireb2tm1.1Mwh/Ireb2tm1.1Mwh
involves: 129P2/OlaHsd * C57BL/6 * SJL
no abnormal phenotype detected J:103414
Ireb2tm1.2Mwh/Ireb2tm1.2Mwh
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL
abnormal duodenum morphology J:103414
abnormal erythrocyte morphology J:103414
abnormal iron homeostasis J:103414
abnormal locomotor behavior J:103414
decreased erythrocyte cell number J:103414
decreased hematocrit J:103414
decreased hemoglobin content J:103414
decreased spleen iron level J:103414
increased intestinal iron level J:103414
increased liver iron level J:103414
microcytosis J:103414
Ireb2tm1Mwh/Ireb2tm1Mwh
involves: 129P2/OlaHsd * C57BL/6J
abnormal erythrocyte morphology J:105124
abnormal iron homeostasis J:105124
abnormal locomotor behavior J:103414
normal behavior/neurological phenotype J:105124
decreased hematocrit J:105124
decreased hemoglobin content J:105124
decreased mean corpuscular volume J:105124
decreased spleen iron level J:105124
increased intestinal iron level J:105124
increased liver iron level J:105124
microcytosis J:105124
Ireb2tm1Roua/Ireb2tm1Roua
B6.Cg-Ireb2tm1Roua
decreased hematocrit J:176655
decreased hemoglobin content J:176655
decreased mean corpuscular hemoglobin J:176655
decreased mean corpuscular hemoglobin concentration J:176655
decreased mean corpuscular volume J:176655
decreased spleen iron level J:176655
increased liver iron level J:176655
microcytosis J:176655
Ireb2tm1Roua/Ireb2tm1Roua
involves: C57BL/6
abnormal cerebellum morphology J:67313
abnormal corpora quadrigemina morphology J:67313
abnormal gait J:67313
abnormal iron homeostasis J:87889
abnormal locomotor behavior J:67313
abnormal posture J:67313
abnormal thalamus morphology J:67313
abnormal vestibular system physiology J:67313
ataxia J:67313
bradykinesia J:67313
decreased grip strength J:67313
decreased Purkinje cell number J:67313
impaired balance J:67313
increased brain iron level J:67313
increased circulating ferritin level J:67313
increased intestinal iron level J:67313
increased liver iron level J:67313
kyphosis J:67313
normal liver/biliary system phenotype J:67313
Purkinje cell degeneration J:67313
tremors J:67313

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory