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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Secisbp2
SECIS binding protein 2
MGI:1922670
22 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Secisbp2tm1.1Amdu/Secisbp2tm1.2Amdu
B6(129S4)-Gt(ROSA)26Sortm1(cre/ERT2)Tyj Secisbp2tm1.1Amdu Secisbp2tm1.2Amdu
abnormal enzyme/coenzyme activity J:251875
abnormal pituitary gland physiology J:251875
abnormal thyroid hormone level J:251875
decreased body weight J:251875
decreased triiodothyronine level J:251875
increased circulating thyroid-stimulating hormone level J:251875
increased thyroxine level J:251875
infertility J:251875
premature death J:251875
Secisbp2tm1.2Amdu/Secisbp2tm1.2Amdu
B6(129S4)-Secisbp2tm1.2Amdu
prenatal lethality, complete penetrance J:251875
Secisbp2tm1a(EUCOMM)Wtsi/Secisbp2+
involves: C57BL/6N
abnormal selenium level J:213080
normal homeostasis/metabolism phenotype J:213080
normal reproductive system phenotype J:213080
Secisbp2tm1a(EUCOMM)Wtsi/Secisbp2+
Not Specified
increased NK cell number J:165965
Secisbp2tm1a(EUCOMM)Wtsi/Secisbp2tm1a(EUCOMM)Wtsi
involves: C57BL/6N
embryonic growth arrest J:213080
embryonic growth retardation J:213080
embryonic lethality between implantation and placentation, incomplete penetrance J:213080
embryonic lethality during organogenesis, incomplete penetrance J:213080
preweaning lethality, complete penetrance J:213080
Secisbp2tm1c(EUCOMM)Wtsi/Secisbp2tm1c(EUCOMM)Wtsi
C57BL/6N-Secisbp2tm1a(EUCOMM)Wtsi/H
abnormal retina morphology J:211773
decreased caudal vertebrae number J:211773
Secisbp2tm1c(EUCOMM)Wtsi/Secisbp2tm1c(EUCOMM)Wtsi
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: C57BL/6 * C57BL/6N * DBA
normal liver/biliary system phenotype J:213080
Secisbp2tm1d(EUCOMM)Wtsi/Secisbp2tm1d(EUCOMM)Wtsi
involves: C57BL/6N
preweaning lethality, complete penetrance J:213080

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory