66 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rptortm1.1Dmsa/Rptortm1.1Dmsa Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ involves: 129S/SvEv * C57BL/6 * DBA	abnormal hepatocyte morphology	J:167208
	abnormal liver physiology	J:167208
	increased circulating ketone body level	J:167208
	small liver	J:167208
Rptortm1.1Dmsa/Rptortm1.1Dmsa Tg(Amh-cre)8815Reb/0 involves: 129S/SvEv * 129S1/SvImJ * C57BL/6 * FVB/N	abnormal cell cytoskeleton morphology	J:268375
	abnormal male germ cell physiology	J:268375
	abnormal peritubular myoid cell morphology	J:268375
	abnormal seminiferous tubule epithelium morphology	J:268375
	abnormal seminiferous tubule morphology	J:268375
	abnormal Sertoli cell barrier morphology	J:268375
	abnormal spermatid morphology	J:268375
	abnormal spermiogenesis	J:268375
	abnormal testis development	J:268375
	azoospermia	J:268375
	decreased epididymis weight	J:268375
	decreased male germ cell number	J:268375
	decreased Sertoli cell number	J:268375
	decreased testis weight	J:268375
	ectopic Sertoli cells	J:268375
	increased testis apoptosis	J:268375
	male infertility	J:268375
	seminiferous tubule degeneration	J:268375
	testis degeneration	J:268375
Rptortm1.1Rueg/Rptor+ involves: 129S1/SvImJ * BALB/cJ * C57BL/6J	abnormal cell differentiation	J:143749
Rptortm1.1Rueg/Rptortm1.1Rueg involves: 129S1/SvImJ * BALB/cJ * C57BL/6J	embryonic lethality, complete penetrance	J:143749
Rptortm1Ahir/Rptortm1Ahir Tg(Itgax-cre)1-1Reiz/0 B6.Cg-Rptortm1Ahir Tg(Itgax-cre)1-1Reiz	decreased colon length	J:188676
	increased dendritic cell number	J:188676
	increased susceptibility to induced colitis	J:188676
	increased susceptibility to weight loss	J:188676
Rptortm1Lex/Rptortm1Lex involves: 129S5/SvEvBrd	preweaning lethality, complete penetrance	J:103485
Rptortm1Lex/Rptortm1Lex involves: 129S/SvEvBrd	abnormal trophoblast giant cell morphology	J:137592
	decreased inner cell mass proliferation	J:137592
	embryonic lethality between implantation and somite formation, complete penetrance	J:137592
Rptortm1Rueg/Rptortm1Rueg Tg(ACTA1-cre)1Mll/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal muscle cell glucose uptake	J:143748
	abnormal muscle morphology	J:143748
	abnormal muscle physiology	J:143748
	decreased body weight	J:143748
	decreased muscle weight	J:143748
	decreased total body fat amount	J:143748
	dystrophic muscle	J:143748
	impaired exercise endurance	J:143748
	increased lean body mass	J:143748
	increased skeletal muscle glycogen level	J:143748
	kyphosis	J:143748
	premature death	J:143748
	skeletal muscle interstitial fibrosis	J:143748
Rptortm1Rueg/Rptortm1Rueg Tg(Fabp4-cre)1Rev/0 involves: 129S1/SvImJ * C57BL/6J	decreased adiponectin level	J:143749
	decreased body weight	J:143749
	decreased brown adipose tissue amount	J:143749
	decreased circulating cholesterol level	J:143749
	decreased circulating glucose level	J:143749
	decreased circulating insulin level	J:143749
	decreased circulating leptin level	J:143749
	decreased litter size	J:143749
	decreased liver triglyceride level	J:143749
	decreased locomotor activity	J:143749
	decreased susceptibility to diet-induced obesity	J:143749
	decreased total fat pad weight	J:143749
	decreased white fat cell number	J:143749
	decreased white fat cell size	J:143749
	normal digestive/alimentary phenotype	J:143749
	normal homeostasis/metabolism phenotype	J:143749
	improved glucose tolerance	J:143749
	increased lean body mass	J:143749
	increased oxygen consumption	J:143749
	reduced female fertility	J:143749
Rptortm2b(EUCOMM)Wtsi/Rptor+ C57BL/6N-Rptortm2b(EUCOMM)Wtsi/H	abnormal sinus arrhythmia	J:211773
Rptortm2b(EUCOMM)Wtsi/Rptortm2b(EUCOMM)Wtsi C57BL/6N-Rptortm2b(EUCOMM)Wtsi/H	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773