Muc5b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Muc5b
mucin 5, subtype B, tracheobronchial
MGI:1921430

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Muc5b^em1(IMPC)Mbp/Muc5b^em1(IMPC)Mbp C57BL/6N-Muc5b^em1(IMPC)Mbp/MbpMmucd	abnormal liver morphology	J:211773
	abnormal skin morphology	J:211773
	decreased prepulse inhibition	J:211773
	decreased startle reflex	J:211773
	small liver	J:211773
Muc5b^tm1.2Evns/Muc5b^tm1.2Evns B6.129S1-Muc5b^tm1.2Evns	abnormal breathing pattern	J:207159
	abnormal middle ear morphology	J:207159
	abnormal professional antigen presenting cell physiology	J:207159
	decreased interleukin-23 secretion	J:207159
	decreased pulmonary ventilation	J:207159
	hypoxemia	J:207159
	impaired macrophage phagocytosis	J:207159
	impaired mucociliary clearance	J:207159
	increased macrophage apoptosis	J:207159
	increased susceptibility to bacterial infection	J:207159
	increased susceptibility to bacterial infection induced morbidity/mortality	J:207159
	increased susceptibility to otitis media	J:207159
	middle ear effusion	J:207159
	postnatal growth retardation	J:207159
	premature death	J:207159
	respiratory system inflammation	J:207159
	sepsis	J:207159
Tg(Scgb1a1-Muc5b,-AcGFP)#Evns/0 involves: C57BL/6J * C57BL/6N	decreased susceptibility to bacterial infection	J:207159
	normal mortality/aging	J:207159

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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